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GESTRINONE
SynDRA canonical compound SYN0027928 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | Progesterone receptor antagonist |
|---|
| Indication | endometriosis |
|---|
| Disease area | obstetrics/gynecology |
|---|
All known targets
Mechanisms of action (all sources)
- PGR ANTAGONIST
- ESR1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR3C1
- SLC6A4
- PDE4D
- PDE3A
- NR1I2
- ADORA1
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- OPRD1
- NR3C2
- ADORA2A
- OPRK1
- OPRM1
- PTGS2
- SAMHD1
- SLC6A2
- SLC6A3
- TBXA2R
- TDP1
- USP1
- HTR1A
- HRH3
- HRH2
- CCKAR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- ATAD5
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- ESR2
- ESRRA
- GCR
- GLI3
- GPX4
- IFNG
- NF2L2
- NR1H4
- PRGR
- RARA
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Contraceptives, Oral, Hormonal
- Hormones
- Progestins
- Reproductive Control Agents
ATC classes
- G03X · OTHER SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
Cross-references
Synonyms
- dimetriose
- dimetrose
- nemestran
- tridomose
- Gestrinona
- A-46-745
- A-46745
- R-2323
- RU-2323
- Dimetriose
- Dimetrose (TN)
- Nemestran
- Dimetrose
- Tridomose
- Ethylnorgestrienone
- Gestrigone
- R 2323
- Ru-2323
- (8S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- A 46745
- CHEBI:89642
- 13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregna-4,9,11-trien-20-yn-3-one
- 18,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)-
- 1421533RCM
- NCGC00167457-01
- Gestrinonum
- Gestrinonum [INN-Latin]
- Gestrinona [INN-Spanish]
- CAS-16320-04-0
- BRN 5610726
- Gestrinone [USAN:INN:BAN]
- UNII-1421533RCM
- GESTRINONE [MI]
- 13-Ethyl-17-alpha-ethinyl-17-hydroxygon-4,9,11-trien-3-one
- GESTRINONE [INN]
- GESTRINONE [JAN]
- Gestrinone (USAN/INN)
- GESTRINONE [USAN]
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