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MK-2461
SynDRA canonical compound SYN0027717 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | MET |
|---|
| Mechanism of action | VEGFR inhibitor |
|---|
All known targets
- MET
- FGFR1
- FGFR2
- FGFR3
- FLT1
- FLT3
- FLT4
- KDR
- MERTK
- MST1R
- NTRK2
- PDGFRB
Mechanisms of action (all sources)
- FGFR inhibitor
- VEGFR inhibitor
- MET INHIBITOR
- Hepatocyte growth factor receptor inhibitor
- FGFR1 INHIBITOR
- FGFR2 INHIBITOR
- FGFR3 INHIBITOR
- FLT1 INHIBITOR
- FLT3 INHIBITOR
- FLT4 INHIBITOR
- KDR INHIBITOR
- MST1R INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PDGFRA
- PIM1
- PHKG2
- PGRMC1
- PFKP
- PEBP1
- PDXK
- PAK4
- NEK9
- PAK2
- PAICS
- OPA1
- OLA1
- NUAK2
- NQO2
- PIM2
- PIP4K2A
- PIP4K2C
- PKMYT1
- PKN1
- PKN2
- PLK4
- PRKAA1
- PRKACA
- PRKACB
- PRKACG
- PRKAG1
- PRKAG2
- PRKAR2A
- PRKCA
- PRKCB
- PRKCD
- NLK
- NEK3
- PRKCQ
- MAPK11
- MAPK9
- MAPK8
- MAPK7
Cross-references
Synonyms
- MK 2461
- MK2461
- UNII-4200RD53XF
- RefChem:159191
- C24H25N5O5S
- JGEBLDKNWBUGRZ-HXUWFJFHSA-N
- SCHEMBL93526
- GTPL7962
- orb1689093
- SCHEMBL29356324
- SCHEMBL29394185
- SCHEMBL29529144
- CHEBI:230540
- GLXC-90441
- EX-A1566
- SLB87939
- BDBM50347659
- MFCD11977739
- NSC764580
- NSC800795
- s2774
- AKOS027282698
- CCG-264723
- CS-5537
- NSC-764580
- NSC-800795
- SDCCGSBI-0654470.P001
- NCGC00346695-01
- NCGC00346695-02
- NCGC00346695-03
- NCGC00346695-05
- AC-32072
- AS-16288
- DA-65500
- HY-50703
- M4004
- SW219905-1
- T6094
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