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AZD-8055
SynDRA canonical compound SYN0027361 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | MTOR |
|---|
| Mechanism of action | MTOR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- MTOR inhibitor
- Serine/threonine-protein kinase mTOR inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PIK3CA
- FECH
- SYK
- PDGFRB
- PHKG2
- PGRMC1
- PFKP
- PEBP1
- PDXK
- AAK1
- NQO2
- PAK6
- PAK4
- PAK2
- PAICS
- OPA1
- OLA1
- NUAK2
- PASK
- PIK3CG
- PIM1
- PIM2
- PRKCA
- PRKAR2A
- PRKAG2
- PRKAG1
- PRKACG
- PRKACB
- PRKACA
- PRKAA1
- PLK4
- PKN3
- PKN2
- PKN1
- PKMYT1
- PIP4K2C
- PIP4K2A
- NTRK1
- NLK
- PRKCD
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- GPX1
- GPX4
- KSYK
- MAPKAP1
- MLST8
- NSD2
- PIK3R1
- RICTOR
- RPTOR
Cross-references
Synonyms
- AZD 8055
- AZ-12600000
- AZD8055
- [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
- (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
- UNII-970JJ37FPW
- 970JJ37FPW
- CHEMBL1801204
- AK109550
- (5-(2,4-Bis((S)-3-methylmorpholino)pyrido-[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
- (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol
- [5-[2,4-bis((3s)-3-methylmorpholin -4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
- (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol.
- (5-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol
- [5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
- MLS006010169
- SCHEMBL298416
- GTPL7714
- CHEBI:91329
- EX-A044
- AZD 8055 [WHO-DD]
- DTXSID001020704
- AMY24189
- BCP02171
- EX-A1549
- BDBM50348452
- MFCD16660191
- NSC758871
- NSC799351
- s1555
- ZINC52509466
- AKOS016009126
- BCP9000367
- CCG-264912
- CS-0067
- DB12774
- NSC-758871
- NSC-799351
- SS-4787
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