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RANITIDINE
SynDRA canonical compound SYN0027257 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH2 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | heartburn |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- HRH2
- ACHE
- Hrh2
- SLC22A2
- SLC47A1
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH2 ANTAGONIST
- Histamine H2 receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM3
- CHRM2
- CHRM1
- HRH3
- DRD2
- SLC6A4
- MC5R
- MAPK14
- MAPK3
- MC3R
- MC4R
- MMP9
- MLNR
- MMP1
- MAOA
- NFKB1
- NPY1R
- NPY2R
- MAPK1
- LCK
- LMNA
- NTSR1
- KCNH2
- KAT2A
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH1
- HMGCR
- HIF1A
- GIPR
- NR3C1
- ABCB1
- OPRD1
- GCGR
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACES
- ATP4A
- ATP4B
- CP1A2
- CP2D6
- CP3A7
Drug classes
- Histamine H2 Receptor Antagonists
- Anti-Ulcer Agents
- Gastrointestinal Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H2 Antagonists
- Neurotransmitter Agents
- Histamine-2 Receptor Antagonist
ATC classes
- A02B · DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Cross-references
Synonyms
- RANITIDINE HYDROCHLORIDE
- TRITEC
- ZANTAC
- ZANTAC 150
- ZANTAC 25
- ZANTAC 300
- ZANTAC 75
- ZANTAC IN PLASTIC CONTAINER
- Zantac
- zantac
- zenetac
- ranitidine hydrochloride
- ranitidine HCl
- Ranitidina
- NSC-757851
- Achedos
- Acidex
- Alquen
- Atural
- Axoban
- Biotidin
- Coralen
- Curan
- Duractin
- Ezopta
- Fendibina
- Gastrial
- Gastridina
- Gastrolav
- Gastrosedol
- Istomar
- Kuracid
- Logast
- Mauran
- Melfax
- Microtid
- Noctone
- Ptinolin
Reported adverse events
- Headache
- Rash
- Constipation
- Stevens-Johnson syndrome
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