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INDOBUFEN
SynDRA canonical compound SYN0026819 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Primary target(s) | PTGS2 |
| Mechanism of action | Platelet aggregation inhibitor |
| Indication | thrombosis |
| Disease area | hematology |
All known targets
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- Platelet aggregation inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- HTR1A
- ADRA1A
- ADORA1
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR3C1
- HRH2
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HRH3
- HRH1
- ADORA2A
- GHSR
- ADORA3
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- BDKRB2
- CCKAR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2CJ
- CP2D6
- ESRRA
- HDAC9
- RARA
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Hematologic Agents
- Peripheral Nervous System Agents
- Platelet Aggregation Inhibitors
- Sensory System Agents
ATC classes
- B01A · ANTITHROMBOTIC AGENTS
Cross-references
Synonyms
- ibustrin
- K-3920
- Indobufene
- Ibustrin
- K-2930
- Indobufenum
- K 3920
- 2-(4-(1-Oxo-2-isoindolinyl)phenyl)butyric acid
- 6T9949G4LZ
- DTXCID8031578
- 1-Oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline
- RefChem:148170
- B01AC10
- Indobufen [INN]
- 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid
- 2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid
- MFCD00572250
- Indobufen (INN)
- (2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid
- s5019
- 2-[4-(1-oxoisoindolin-2-yl)phenyl]butanoic acid
- Indobufene [INN-French]
- Indobufenum [INN-Latin]
- (+/-)-2-[p-(1-oxo-2-isoindolinyl)phenyl]butyric acid
- UNII-6T9949G4LZ
- (+/-)-2-(P-(1-OXO-2-ISOINDOLINYL)PHENYL)BUTYRIC ACID
- AYDXAULLCROVIT-UHFFFAOYSA-N
- EINECS 264-364-4
- Indobufen (Standard)
- Enamine_001568
- INDOBUFEN [MI]
- INDOBUFEN [MART.]
- INDOBUFEN [WHO-DD]
- Oprea1_118499
- SCHEMBL140517
- orb1308195
- (+-)-2-(4-(1-Oxo-2-isoindolinyl)phenyl)buttersaeure
- SCHEMBL29546086
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