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GIMERACIL
SynDRA canonical compound SYN0026636 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | DPYD |
|---|
| Mechanism of action | Dihydropyrimidine dehydrogenase inhibitor |
|---|
| Indication | gastric adenocarcinoma |
|---|
| Disease area | oncology |
|---|
All known targets
Mechanisms of action (all sources)
- Dihydropyrimidine dehydrogenase inhibitor
- DPYD INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- NR1I2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR3C1
- HRH1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HRH2
- HDAC6
- ADORA2A
- CCKAR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
Cross-references
Synonyms
- 5-chloro-2,4-dihydroxypyridine
- gimestat
- 5-Chloro-4-hydroxy-2-pyridone
- Gimeracilo
- Gimestat
- Gimeracil component of teysuno
- 5-Chloro-2,4-dihydroxypyridine
- 5-chloropyridine-2,4-diol
- 5-Chloro-4-hydroxy-2(1H)-pyridone
- 5-Chloro-4-hydroxy-2(1H)-pyridinone
- Gimeracil [INN]
- 5-Chloro-4-hydroxy-1H-pyridin-2-one
- 5-Chloro-2,4-pyridinediol
- 5-chloro-2-hydroxypyridin-4(1H)-one
- 2(1H)-Pyridinone, 5-chloro-4-hydroxy-
- 5-CHLORO-4-HYDROXY-2-PYRIDONE
- UA8SE1325T
- 5-CHLORO-4-HYDROXYPYRIDIN-2(1H)-ONE
- MFCD08458352
- NCGC00181011-01
- Cdhp compound
- CAS-103766-25-2
- UNII-UA8SE1325T
- Gimeracil (CDHP)
- Gimeracil (JAN/INN)
- GIMERACIL [JAN]
- GIMERACIL [MI]
- GIMERACIL [WHO-DD]
- GIMERACIL IMPURITY 1
- GIMERACIL [EMA EPAR]
- SCHEMBL124438
- Ts-1 (TN)
- CHEMBL1730601
- DTXSID8046799
- Gimeracil, >=98% (HPLC)
- CHEBI:31652
- AMY2406
- TEYSUNO COMPONENT GIMERACIL
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