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SU-014813
SynDRA canonical compound SYN0026620 — structure-anchored drug synonym record
Clinical phase
Phase 2
Primary target(s)
KDR
Mechanism of action
pdgfr tyrosine kinase receptor inhibitor, vegfr inhibitor
All known targets
KDR
FLT1
FLT3
FLT4
KIT
PDGFRA
PDGFRB
Mechanisms of action (all sources)
FLT1 INHIBITOR
Vascular endothelial growth factor receptor inhibitor
FLT4 INHIBITOR
KDR INHIBITOR
PDGFRB INHIBITOR
Platelet-derived growth factor receptor inhibitor
PDGFRA INHIBITOR
KIT INHIBITOR
Stem cell growth factor receptor inhibitor
FLT3 INHIBITOR
Tyrosine-protein kinase receptor FLT3 inhibitor
pdgfr tyrosine kinase receptor inhibitor, vegfr inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
FGFR1
AAK1
PEBP1
PIK3CG
PIK3CD
PIK3CB
PIK3CA
PIK3C2G
PIK3C2B
PI4KB
PHKG2
PHKG1
PGRMC1
PFKP
PDXK
PRKCZ
PDPK1
PCYT1A
PASK
PAK6
PAK5
PAK4
PAK3
PAK2
PAK1
PAICS
OXSR1
OPA1
PIM1
PIM2
PIM3
PIP4K2A
PRKCI
PRKCH
PRKCE
PRKCD
PRKCB
PRKCA
PRKAR2A
PRKAG2
Cross-references
PubChem CID:
73755145
ChEMBL:
CHEMBL1721885
TTD: D09DJU
Synonyms
Su-14813
SU 14813
SU14813
5-((5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
SU014813
ZZ6VH5MZ17
RefChem:1099116
VEGFR2/PDGFR/c-Kit/Flt-3 Inhibitor SU014813
SU14813 double bond Z
UNII-ZZ6VH5MZ17
C23H27FN4O4
MFCD16495822
SCHEMBL902507
orb2308701
BDBM31095
cid_10138259
HY-10501B
NSC800936
AKOS025404896
CS-1159
NSC-800936
NCGC00379021-01
PA-10138259
T85345
SU14813 double bond Z|452105-23-6|SU 14813
5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
AKOS025404884
SU14813 maleate
DA-67817
SU14813 (maleate)
orb1679057
5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2Z)-2-butenedioate
SU-014813 MALEATE
C27H31FN4O8
orb1146448
MFCD24682713
HY-10501A
CS-0649
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