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NICERITROL
SynDRA canonical compound SYN0026533 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HCAR2 |
|---|
| Mechanism of action | NAD precursor |
|---|
| Indication | hyperlipidemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
- HCAR2
- HCAR3
- HCAR1
- DGAT2
- NNMT
- QPRT
- NAMPT
- Hcar2
- APP
Mechanisms of action (all sources)
- NAD precursor
- NAD precursor with lipid lowering effects
- HCAR1 AGONIST
- HCAR2 FULL AGONIST
- HCAR3 FULL AGONIST
- DGAT2 INHIBITOR
- HCAR2 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antimetabolites
- Hypolipidemic Agents
- Lipid Regulating Agents
- Nicotinic Acid
- Cardiovascular Agents
- Vasodilator Agents
- Micronutrients
- Vitamin B Complex
- Vitamins
- Vitamin B
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
- C04A · PERIPHERAL VASODILATORS
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- pentaerythritoltetranicotinate
- niceritrol tetrahydrochloride
- nicotinic acid neopentanetetrayl ester
- pentaerythritol tetranicotinate
- perycit
- Pentaerithritol tetranicotinate
- Perycit
- Pentaerythritoltetranicotinate
- Pentaerythritol tetranicotinate
- Niceritrolum
- F54EHJ34MV
- DTXCID303364
- niceritrolo
- Tetrahydrochloride, Niceritrol
- Tetranicotinate, Pentaerythritol
- RefChem:389147
- C10AD01
- Bufor;Perycit;8-AL
- Bufor
- MFCD00215982
- NCGC00185747-01
- Cardiolipol
- CAS-5868-05-3
- SK 1 (Pharmaceutical)
- Niceritrolum [INN-Latin]
- Niceritrol [INN:BAN:DCF:JAN]
- KUEUWHJGRZKESU-UHFFFAOYSA-N
- C29H24N4O8
- EINECS 227-519-7
- Perycit (TN)
- BRN 0377170
- NICERITROL [MI]
- NICERITROL [INN]
- NICERITROL [JAN]
- NICOTINIC ACID, NEOPENTANETETRAYL ESTER
- Niceritrol (JP18/INN)
- UNII-F54EHJ34MV
- NICERITROL [MART.]
Reported adverse events
- Atrial fibrillation
- Dyspepsia
- Headache
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