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RAMOSETRON
SynDRA canonical compound SYN0026002 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HTR3A |
|---|
| Mechanism of action | serotonin receptor antagonist |
|---|
| Indication | irritable bowel syndrome | nausea | vomiting |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- HTR3A
- HTR3B
- HTR3C
- HTR3D
- HTR3E
Mechanisms of action (all sources)
- HTR3A ANTAGONIST
- HTR3E ANTAGONIST
- HTR3B ANTAGONIST
- HTR3D ANTAGONIST
- HTR3C ANTAGONIST
- serotonin receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC6A4
- ADRA2A
- ADRA2B
- KCNH2
- ABCB1
- NR1I2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- MAOA
- MC3R
- MLNR
- NPY1R
- OPRD1
- NR3C1
- HRH1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- HRH2
- HDAC6
- ADORA1
- CCKAR
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- GLI3
Drug classes
- Antiemetics
- Central Nervous System Agents
- Gastrointestinal Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Serotonin Agents
- Serotonin Antagonists
Cross-references
Synonyms
- YM-060
- ibsetron hydrochloride
- ibsetron
- ramosetron hydrochloride
- irribow
- ibsetron HCl
- ramosetron HCl
- UNII-7ZRO0SC54Y
- Ramosetron [INN]
- 7ZRO0SC54Y
- CHEMBL1643895
- Ramosetron (INN)
- (1-methylindol-3-yl)-[(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]methanone
- Nor-YM 060
- SCHEMBL16701
- GTPL2301
- DTXSID0043842
- NTHPAPBPFQJABD-LLVKDONJSA-N
- MolPort-019-991-383
- CHEBI:135156
- ZINC5116719
- AC1L3355
- BDBM50334454
- 8235AH
- AKOS015896003
- SB19072
- DB09290
- SC-92398
- AJ-53160
- LS-187182
- TL8000762
- R-146
- FT-0651831
- D08466
- A806353
- (-)-(R)-1-Methylindol-3-yl-4,5,6,7-tetrahydro-5-benzimidazolyl ketone
- Nasea (TN)
- YM060
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