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ABAMECTIN COMPONENT B1A
SynDRA canonical compound SYN0025822 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | GABBR1 | GABBR2 |
|---|
| Mechanism of action | benzodiazepine receptor agonist |
|---|
| Indication | gastrointestinal parasites |
|---|
| Disease area | infectious disease |
|---|
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- ADORA3
- ESR2
- ESR1
- ACHE
- NR3C1
- NR1H4
- NPY2R
- NPY1R
- NFKB1
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MAPK3
- MC3R
- OPRK1
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- HTR6
- HTR2C
- HTR2B
- OPRD1
- OPRM1
- HRH2
- SLC6A2
- VDR
- TST
- TP53
- THRB
- TDP1
- TBXAS1
- TACR2
- TACR1
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CASP3
- CASP7
- CP19A
- CP1A2
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- ESRRA
- GCR
- GLI3
- GPX4
- NF2L2
- PRGR
- RARA
Drug classes
- Anthelmintics
- Insecticides
Cross-references
Synonyms
- 5-o-demethylavermectin a1a
- Abamectin b1a
- Avermectin a1a, 5-o-demethyl-
- Avermectin b1a
- avermectin B1a
- Abamectin B1a
- 5-O-Demethylavermectin A1a
- Avermectin B(1)a
- Avermectin A1a, 5-O-demethyl-
- Antibiotic C 076B1a
- Caswell No. 063AB
- Abamectin komponente B1a
- K54ZMM929K
- CHEBI:29534
- RefChem:6604
- C-076
- DTXCID403892
- avermectin B1a (purity >=80 %)
- MFCD01939385
- C48H72O14
- Ivermectin EP Impurity A
- DSSTox_CID_3892
- DSSTox_RID_77221
- DSSTox_GSID_23892
- Abamectine [French]
- Abamectinum [Latin]
- Abamectina [Spanish]
- EINECS 265-610-3
- Antibiotic C 076A1a, 5-O-demethyl-
- UNII-K54ZMM929K
- NCGC00094556-01
- Avermectin A(sub 1a), 5-O-demethyl-
- Avermectin B1a (>85%)
- SCHEMBL302300
- orb1299666
- RRZXIRBKKLTSOM-XPNPUAGNSA-N
- MSK25086
- Tox21_111295
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