← SynDRA

FATOSTATIN

SynDRA canonical compound SYN0025754 — structure-anchored drug synonym record

All known targets

• SREBF1
• SREBF2

Mechanisms of action (all sources)

• SREBP inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ALDH1A1
• KDM4A
• TDP1
• SMPD1
• SMAD3
• PTH1R
• MAPT
• L3MBTL1
• IDH1
• ATAD5
• GMNN
• CGA
• CBX1
• BAZ2B
• ATXN2
• ATM
• USP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• FAS
• MDR1

Cross-references

• PubChem CID: 1889993
• ChEMBL: CHEMBL1621019
• ChEBI: 95052
• LINCS BRD: BRD-K99696746

Synonyms

• RefChem:140015
• Fatostatin A
• 2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole
• Pyridine, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-
• 4-(4-methylphenyl)-2-(2-propylpyridin-4-yl)-1,3-thiazole
• 4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-propylpyridine
• 2-(2-propyl-4-pyridyl)-4-(p-tolyl)thiazole
• MLS000332366
• SMR000221636
• 2-Propyl-4-(4-p-tolyl-thiazol-2-yl)-pyridine
• 2-(2-propyl-4-pyridyl)-4-(p-tolyl)thiazole;hydrobromide
• MFCD02376000
• Oprea1_120708
• orb1298230
• SCHEMBL2742732
• SCHEMBL29458338
• BDBM78179
• CHEBI:95052
• cid_2850562
• ZROSUBKIGBSZCG-UHFFFAOYSA-N
• ALBB-033720
• s9785
• STK326446
• AKOS005434229
• CS-5810
• AC-35652
• BS-15072
• DA-53125
• DA-63386
• HY-14452
• ST45157155
• T9266
• D84076
• F861655
• 4-(4-methylphenyl)-2-(2-propyl-4-pyridinyl)thiazole
• 4-(4-methylphenyl)-2-(2-propyl(4-pyridyl))-1,3-thiazole
• 4-(4-METHYLPHENYL)-2-(2-PROPYL-4-PYRIDYL)-1,3-THIAZOLE