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NAFRONYL
SynDRA canonical compound SYN0025752 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | adrenergic receptor antagonist |
|---|
| Indication | claudication |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- adrenergic receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- OPRM1
- CHRM2
- PTGS1
- KDR
- MAOA
- PDE3A
- PDE4A
- PGR
- POLI
- RGS4
- KDM4A
- SAMHD1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- KDM4E
- ABCB11
- ACHE
- CYP3A4
- ADORA3
- ADRA1A
- ADRA2A
- AR
- BAZ2B
- CBX1
- CHRM1
- DRD1
- HTR2B
- DRD3
- ESR1
- F2
- GLP1R
- HDAC6
- HRH3
- HTR1A
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- CP2D6
- CP3A4
- CP3A7
- JUN
- MDR1
- NTM1A
- NTMT1
Drug classes
- Cardiovascular Agents
- Neurotransmitter Agents
- Serotonin Agents
- Serotonin Antagonists
- Vasodilator Agents
ATC classes
- C04A · PERIPHERAL VASODILATORS
Cross-references
Synonyms
- naftidrofuryl
- naftidrofurile
- nafronyl oxalate
- naphtidrofuryl
- naftidrofuryl oxalate
- naftidrofuryl hydrogen oxalate
- Naftidrofuryl
- Naftidrofurilo
- Drosunal
- Dubimax
- Gevatran
- Nafronyl oxalate
- Naftidrofuryl oxalate
- Nafronyl oxalate salt
- 2-(Diethylamino)ethyl 3-(naphthalen-1-yl)-2-((tetrahydrofuran-2-yl)methyl)propanoate oxalate
- Naftidrofuryl (oxalate)
- Dusodril
- Praxilene
- Iridus
- LS 121
- EU-1806
- DSSTox_RID_80935
- DSSTox_CID_25533
- DSSTox_GSID_45533
- CHEMBL1439099
- alpha-[1-Naphthylmethyl]-2-tetrahydrofuranpropionic acid diethylaminoethyl ester
- SMR000539007
- Nafronyl oxalate salt, analytical standard
- CAS-3200-06-4
- NSC225233
- Naphtidrofuryl
- Tridus
- LS 84
- 2-(Diethylamino)ethyl 3-(naphthalen-1-yl)-2-((tetrahydrofuran-2-yl)methyl)propanoate
- 42H8PQ0NMJ
- 3-(1-Naphthyl)-2-tetrahydrofurfurylpropionic acid 2-(diethylamino)ethyl ester
- 2-Furanpropanoic acid, tetrahydro-alpha-(1-naphthalenylmethyl)-, 2-(diethylamino)ethyl ester
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