← SynDRA
OSI-930
SynDRA canonical compound SYN0025686 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | KIT |
|---|
| Mechanism of action | VEGFR inhibitor |
|---|
All known targets
- KDR
- KIT
- FLT1
- FLT4
- CSF1R
- PDGFB
- PDGFRB
- RAF1
Mechanisms of action (all sources)
- KIT INHIBITOR
- VEGFR inhibitor
- Stem cell growth factor receptor inhibitor
- FLT1 INHIBITOR
- Vascular endothelial growth factor receptor inhibitor
- FLT4 INHIBITOR
- KDR INHIBITOR
- CSF1R INHIBITOR
- RAF1 INHIBITOR
- KDR MODULATOR
- KIT MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PDXK
- PASK
- PAK6
- PAK4
- PAICS
- OPA1
- NUAK2
- NTRK1
- NQO2
- NLK
- NEK9
- NEK3
- NEK2
- NEK1
- NDUFA13
- NAT10
- PCYT1A
- PGRMC1
- ABL1
- PHKG2
- PRKAG2
- PRKAG1
- PRKACB
- PRKACA
- PRKAA1
- PLK4
- PLK1
- PKN3
- PKN2
- PKN1
- PKMYT1
- PIP4K2C
- PIP4K2A
- PIM2
- PIM1
- MYLK3
- MYLK
- MYH14
- MYH10
Cross-references
Synonyms
- OSI 930
- OSI930
- OSI-930 is a multi-targeted tyrosine kinase inhibitor
- 3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide
- G1PEG5Q9Y2
- RefChem:168670
- Tyrosine Kinase Inhibitor OSI-930
- C22H16F3N3O2S
- UNII-G1PEG5Q9Y2
- MFCD11100358
- MLS006010277
- SCHEMBL633719
- GTPL9383
- orb1305252
- OSI 930 [WHO-DD]
- SCHEMBL29352171
- CHEBI:91433
- GLXC-90038
- HMS3295O11
- HMS3654H03
- EX-A2118
- OSI 930?
- BDBM50356877
- EBC-11378
- NSC766887
- NSC800811
- s1220
- AKOS026750567
- CCG-264867
- CS-0174
- NSC-766887
- NSC-800811
- SB16588
- SDCCGSBI-0654359.P001
- NCGC00263159-01
- NCGC00263159-07
- NCGC00263159-08
- NCGC00263159-10
Look up OSI-930 in the interactive SynDRA portal →