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ALFACALCIDOL

SynDRA canonical compound SYN0025641 — structure-anchored drug synonym record

All known targets

• VDR
• CYP27B1
• SLC6A2
• CYP3A5
• CYP2R1
• GC
• Vdr
• vdra

Mechanisms of action (all sources)

• Vitamin D receptor agonist
• VDR AGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• AGTR1
• ACHE
• KCNH2
• MMP9
• MMP1
• MLNR
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• MAOA
• LCK
• HTR6
• NPY2R
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH3
• HRH2
• HRH1
• HMGCR
• HDAC6
• GHSR
• NPY1R
• NR1I2
• FLT1
• PTGS2
• TDP1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC29A1
• SIGMAR1
• PTPRC

Drug classes

• Bone Density Conservation Agents
• Calcium Channel Agonists
• Calcium-Regulating Hormones and Agents
• Cardiovascular Agents
• Membrane Transport Modulators
• Micronutrients
• Vasoconstrictor Agents
• Vitamins
• Vitamin D3 Analog

ATC classes

• A11C · VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO
• DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
• D05A · ANTIPSORIATICS FOR TOPICAL USE

Cross-references

• PubChem CID: 5282181
• ChEMBL: CHEMBL1601669
• DrugBank: DB01436
• ChEBI: CHEBI:31186
• KEGG: D01518
• RxNorm: 12062
• PDB: M9B
• Wikipedia: Alfacalcidol
• LINCS BRD: BRD-K93433262

Synonyms

• 1alpha-Hydroxycholecalciferol
• alfarol
• alphacalcidol
• einsalpha
• alpha-calcidol
• 1-hydroxycholecalciferol
• 1.alpha.-hydroxycholecalciferol
• .alpha.-calcidol
• 1-alpha-vitamin d
• 1-hydroxyvitamin d3
• 1.alpha-hydroxycholecalciferol
• 1.alpha.(oh)d3
• 1.alpha.-hydroxyvitamin d3
• Alfarol
• Alpha d3
• Alphacalcidol
• Alpharol
• Alsiodol
• Bondiol
• Einsalpha
• Oxydevit
• Tevabone
• Un alfa
• Un alpha
• Alfa d
• Etalpha
• One-alpha
• 1-Hydroxycholecalciferol
• 1alpha-Hydroxyvitamin D3
• EinsAlpha
• 1-Hydroxyvitamin D3
• alpha-Calcidol
• One-Alpha
• Alfacalcidolum
• 1alpha-Hydroxy-vitamin D3
• Vitamin D3, 1alpha-Hydroxy-
• 1.alpha.-Hydroxyvitamin D3
• 1-alpha-hydroxy-vitamin D3

Reported adverse events

• Hypersensitivity
• Discomfort