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AMPIROXICAM
SynDRA canonical compound SYN0025569 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | pain relief |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- PTGS1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2B
- ACHE
- KCNH2
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KAT2A
- MMP9
- HTR6
- HTR3A
- HTR2C
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- MMP1
- NPY1R
- FYN
- NPY2R
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SIGMAR1
- PTPRC
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cyclooxygenase Inhibitors
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
- Nonsteroidal Anti-inflammatory Drug
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
- M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
- S01B · ANTIINFLAMMATORY AGENTS
Cross-references
Synonyms
- flucam
- CP 65703
- Flucam
- CP-65,703
- CP-65703
- NSC-759807
- Nacyl
- Nasil
- Ampiroxicamum
- 0PV32JZB1J
- NSC 759807
- DTXCID4026474
- CHEBI:31210
- RefChem:557922
- NCGC00164605-01
- Ampiroxicamum [Latin]
- CAS-99464-64-9
- UNII-0PV32JZB1J
- BRN 5184713
- Ampiroxicam [INN:BAN:JAN]
- Flucam (TN)
- MFCD00866079
- Ampiroxicam (Standard)
- AMPIROXICAM [MI]
- AMPIROXICAM [INN]
- AMPIROXICAM [JAN]
- Ampiroxicam (JP18/INN)
- AMPIROXICAM [MART.]
- SCHEMBL49363
- AMPIROXICAM [WHO-DD]
- MLS001424306
- orb1300813
- Ampiroxicam - Bio-X trade mark
- SCHEMBL21357883
- SCHEMBL29385297
- Ampiroxicam, >=98% (HPLC)
- HMS2052J03
- HMS2090I13
Reported adverse events
- Bleeding
- GI bleed
- Perforation
- Ulceration
- Elderly
- Alopecia
- Anxiety
- Asthma
- Conjunctivitis
- Dizziness
- Hypersensitivity
- Pruritus
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