← SynDRA

ETHAVERINE

SynDRA canonical compound SYN0025542 — structure-anchored drug synonym record

Mechanisms of action (all sources)

• calcium channel blocker

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• DRD1
• ADRA1A
• ADORA3
• CHRM1
• PDE3A
• PDE4A
• PDE4D
• ESR1
• ACHE
• MAPK1
• OPRM1
• PGR
• PTGS1
• POLK
• LMNA
• SLC6A2
• SLC6A3
• SLC6A4
• SMN1
• TBXA2R
• TDP1
• TSHR
• MAOA
• HTR2B
• KDR
• KCNH2
• ADRA2A
• ALOX15B
• AR
• CHRM2
• CYP1A2
• CYP2C19
• CYP2C9
• CYP2D6
• CYP3A4
• DRD3
• F2
• GLP1R
• HDAC6
• HRH3

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ACES
• ANDR
• SMAD3
• SMAD2
• PRGR
• NSD2
• NR1I2
• MDR1
• KSYK
• IFNG
• GPR32
• GLI3
• ESRRA
• ESR2
• CREB1
• CP3A7
• CP3A4
• CP2D6
• CP2CJ
• CP2C9
• CP1A2
• SYK

Drug classes

• Parasympatholytics
• Peripheral Nervous System Agents

Cross-references

• PubChem CID: 3280
• ChEMBL: CHEMBL1555736
• ChEBI: CHEBI:94592
• KEGG: D07926
• RxNorm: 24464
• PDB: VIC
• LINCS BRD: BRD-K36756879

Synonyms

• ethquinol
• barbonin
• barbonine
• dyscural
• ethylpapaverine
• ethaverine hydrochloride
• ethaverine HCl
• Etaverina
• Ethquinol
• Ethylpapaverine
• 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinoline
• Ethaverinum
• 1-(3,4-Diethoxybenzyl)-6,7-diethoxyisoquinoline
• 6,7-Diethoxy-1-(3,4-diethoxybenzyl)isoquinoline
• 2H2HC19DYZ
• 1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxyisoquinoline
• RefChem:138373
• DTXCID903009
• Barbonin
• Barbonine
• Dyscural
• Perparine
• Perperine
• Ethaverine [INN]
• Isoquinoline, 6,7-diethoxy-1-(3,4-diethoxybenzyl)-
• ISOQUINOLINE, 1-(3,4-DIETHOXYBENZYL)-6,7-DIETHOXY-
• 6,7-Diaethoxy-1-(3,4-diaethoxybenzyl)isochinolin
• Ethaverine (INN)
• 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline
• Isoquinoline, 1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxy-
• Isoquinoline, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-
• Etaverina [INN-Spanish]
• Ethaverinum [INN-Latin]
• ETHYLPAPAVERINE HYDROCHLORIDE
• NCGC00016557-01
• CAS-985-13-7
• EINECS 207-633-3
• UNII-2H2HC19DYZ