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GW441756X
SynDRA canonical compound SYN0025456 — structure-anchored drug synonym record
| Primary target(s) | NTRK1 |
|---|
| Mechanism of action | Growth factor receptor inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Growth factor receptor inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MINK1
- CHEK2
- PIM3
- HIPK4
- CDK1
- CDK2
- IGF1R
- CDK5
- PIM1
- SRC
- CLK2
- STK3
- INSR
- LYN
- RET
- ROCK1
- LCK
- SGK2
- ROCK2
- IRAK4
- ITK
- PHKG2
- NTRK3
- ALK
- AURKA
- AURKB
- MARK2
- NTRK2
- BLK
- FRK
- FGFR1
- BRSK1
- NEK2
- FER
- GSK3B
- YES1
- MARK3
- PIK3CA
- PRKAA2
- PI4KB
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AAPK1
- KSYK
- VGFR2
- TP53
- ST17A
- MK09
- M4K5
- M4K4
- M4K2
- M3K20
- KS6B1
- CSK21
- KS6A3
- KPCD3
- KPCD2
- KCC2G
- KCC2D
- KC1D
- KC1A
- DYR1A
- VGFR3
Cross-references
Synonyms
- GW-441756
- Kinome_3134
- SCHEMBL5787774
- SCHEMBL29794620
- GLXC-07523
- HMS3244C15
- HMS3244C16
- HMS3244D15
- HMS3268D18
- HMS3747M03
- AKOS024457004
- SB19388
- NCGC00161398-01
- NCGC00165797-01
- NCGC00242139-01
- 3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
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