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PEROSPIRONE
SynDRA canonical compound SYN0025344 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | HTR2A |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
| Indication | bipolar disorder | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- DRD3
- DRD4
- HTR2A
- HTR2C
- Htr2a
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- DRD2 ANTAGONIST
- DRD3 ANTAGONIST
- DRD4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC6A3
- ADRA1A
- ADRA2A
- KCNH2
- OPRM1
- TBXA2R
- CHRM2
- SLC6A4
- DRD1
- HTR1A
- SLC6A2
- PGR
- PDE3A
- PDE4A
- ACHE
- PTGS1
- PTH1R
- MAOA
- SMAD3
- TDP1
- USP1
- NFE2L2
- IDH1
- LMNA
- KDR
- ADORA3
- HTR2B
- HRH3
- HDAC6
- GMNN
- GLP1R
- F2
- ESR1
- CYP3A4
- CHRM1
- CBX1
- ATXN2
- AR
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- AHR
- ANDR
- CP19A
- CP2D6
- CP3A7
- ESRRA
- GLI3
- IDHC
- IL1B
- KCMB1
- NF2L2
- NR1I2
- NSD2
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Psychotropic Drugs
- Tranquilizing Agents
Cross-references
Synonyms
- lullan
- SM 9018
- perospirone hydrochloride
- perospirone hydrochloride dihydrate
- perospirone HCl
- perospirone hydrochloride hydrate
- Perospirona
- Lullan
- SM-9018
- perospirona
- N303OK87DT
- perospironum
- RefChem:171806
- DTXCID3028138
- Perospirone [INN]
- NCGC00164567-01
- UNII-N303OK87DT
- Lullan (Japan)
- Perospirone Free Base
- PEROSPIRONE [MI]
- PEROSPIRONE [WHO-DD]
- SCHEMBL120579
- GTPL7556
- orb1302743
- SCHEMBL30061058
- CHEBI:94777
- HY-B0731A
- GLXC-21078
- HMS3715H10
- MFCD00866669
- s5185
- AKOS025311209
- CCG-221234
- MRF-0000147
- AS-14845
- DB-289872
- CS-0019906
- NS00071002
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