← SynDRA
NITROXOLINE
SynDRA canonical compound SYN0025333 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CTSB | METAP1 | METAP2 | SIRT1 |
|---|
| Mechanism of action | cathepsin inhibitor |
|---|
| Indication | urinary tract infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
- METAP2
- CTSB
- BRD4
- CTH
- Comt
- METAP1
- PTGS2
- SIRT1
Mechanisms of action (all sources)
- METAP2 INHIBITOR
- cathepsin inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- ESR1
- DRD3
- CHRM3
- OPRK1
- CHRM1
- OPRD1
- HRH1
- PDE4D
- HTR2C
- ADRA2C
- ADRA2B
- HTR3A
- MBNL1
- NFE2L2
- MAPT
- NR2E3
- MAOA
- OPRM1
- PDE3A
- PDE4A
- LMNA
- NPC1
- ACHE
- KDM4A
- PGR
- POLI
- PTGS1
- RAB9A
- SLC6A2
- SLC6A3
- SLC6A4
- SMAD3
- SMN1
- SNCA
- TARDBP
- TBXA2R
- TDP1
- USP1
- KDM4E
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3G
- AHR
- SYK
- SMAD2
- SIX1
- RBBP8
- PRGR
- PPARD
- NSD2
- NR1I2
- NR1H4
- NLRP1
- MITF
- MCL1
- KSYK
- JUN
- IDHC
- HSPB1
- HS90A
- GSTO1
- GLI3
- GEMI
- GCR
- G3P
- ESRRA
- ESR2
- CP2C9
- CP19A
- CASP1
- ARNT
- ANDR
- TACC3
Drug classes
- Anti-Infective Agents
- Anti-Infective Agents, Urinary
- Antifungal Agents
ATC classes
- J01X · OTHER ANTIBACTERIALS
Cross-references
Synonyms
- nitroxolin
- noxibiol
- 5-Nitro-8-oxychinoline
- Nitroxolina
- A-82
- NSC-74947
- 5-nitroquinolin-8-ol
- 8-Hydroxy-5-nitroquinoline
- 5-Nitro-8-quinolinol
- 5-Nitro-8-hydroxyquinoline
- 5-Nitrox
- 5-NOK
- 5-Nitro-8-oxyquinoline
- 5NOK
- Nitroxolinum
- NSC 74947
- A8M33244M6
- DTXCID2026284
- CHEBI:67121
- Nicene
- RefChem:166162
- Nitroxolin
- Noxibiol
- Nibiol
- Noxin
- 8-Quinolinol, 5-nitro-
- 5-Nitroxine
- 5-Nitroks
- Nitroxolinum [INN-Latin]
- Nitroxolina [INN-Spanish]
- BAS 58
- MLS000069750
- MFCD00006791
- SMR000059036
- Galinok
- Isinok
- Nicene Forte
- Nitroxoline (INN)
Look up NITROXOLINE in the interactive SynDRA portal →