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OTILONIUM
SynDRA canonical compound SYN0025264 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CACNA1C |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
| Indication | irritable bowel syndrome |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MC3R
- NR1I2
- NPY1R
- MLNR
- DRD3
- DRD2
- OPRK1
- ADORA2A
- KCNH2
- CHRM3
- PDE4D
- CHRM1
- PGR
- GHSR
- AVPR2
- SLC6A2
- SLC6A3
- SLC6A4
- HTR2A
- ADRA2C
- ADRA2B
- HTR2B
- HTR2C
- ADORA3
- MAOA
- ADORA1
- PDE3A
- NR3C1
- OPRD1
- OPRM1
- PTGS2
- SLC29A1
- TBXA2R
- TDP1
- USP1
- KMT2A
- HRH2
- HTR3A
- HTR1A
- ADRA1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACES
- ACM1
- CP2C9
- CP2CJ
- CP2D6
- CP3A7
- CREB1
- GEMI
- IP6K1
- JUN
- NTM1A
- NTMT1
- RARA
- TSHR
- UBP1
Drug classes
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Cholinergic Agents
- Cholinergic Antagonists
- Gastrointestinal Agents
- Membrane Transport Modulators
- Muscarinic Antagonists
- Neurotransmitter Agents
- Parasympatholytics
- Peripheral Nervous System Agents
ATC classes
- A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
Cross-references
Synonyms
- otilonium bromide
- octylonium bromide
- Octylonium
- Otilonium cation
- Otilonium ion
- Otilonium bromide
- Octylonium bromide
- Spasmomen
- Otilonium (bromide)
- SP63
- Ottilonio bromuro [Italian]
- UNII-21HN3N72PV
- Otilonium bromide [INN:BAN]
- Otilonii bromidum [INN-Latin]
- Bromure d'otilonium [INN-French]
- Bromuro de otilonio [INN-Spanish]
- EINECS 247-457-4
- 21HN3N72PV
- Diethyl(2-hydroxyethyl)methylammonium bromide p-(o-(octyloxy)benzamido)benzoate
- Ethanaminium, N,N-diethyl-N-methyl-2-((4-((2-(octyloxy)benzoyl)amino)benzoyl)oxy)-, bromide
- DSSTox_CID_26357
- DSSTox_RID_81559
- NCGC00163507-01
- UNII-6330179ARU
- OTILONIUM [WHO-DD]
- SCHEMBL20352274
- SCHEMBL31646954
- CHEBI:135780
- NCGC00163507-02
- NS00070393
- AB01566869_01
- BRD-K85337334-004-02-6
- 7TB
- octylonium
- SW219209-1
- NS00050510
- DTXCID8026357
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