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LIMANTRAFIN
SynDRA canonical compound SYN0025259 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | NOTCH1 |
|---|
| Mechanism of action | notch signaling inhibitor |
|---|
| Indication | breast cancer |
|---|
| Disease area | oncology |
|---|
All known targets
Mechanisms of action (all sources)
- notch signaling inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- APEX1
- BAZ2B
- GLP1R
- GMNN
- KAT2A
- KDM4E
- NFE2L2
- PIN1
- POLB
- RAB9A
- SMAD3
- TARDBP
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALR
- ATXN2
- COT2
- EPAS1
- HXA9
- KCNQ1
- NCOA2
- NOD1
- NPY1R
- NPY2R
- PSDE
Cross-references
Synonyms
- Limantrafine
- Limantrafina
- 6-(4-(1,1-dimethylethyl)phenoxy)-3-pyridinamine
- CB-103
- 6-(4-tert-butylphenoxy)pyridin-3-amine
- 5-Amino-2-(4-tert-butylphenoxy)pyridine
- 6-(4-(tert-Butyl)phenoxy)pyridin-3-amine
- 6-[4-(tert-butyl)phenoxy]pyridin-3-amine
- UNII-Q5BB91JL0V
- Q5BB91JL0V
- MLS000833648
- CB103
- 6-(4-tert-butylphenoxy)-3-pyridinamine
- SMR000457169
- PubChem13390
- Maybridge1_001148
- Oprea1_231562
- SCHEMBL4638726
- CHEMBL1420319
- BDBM87327
- cid_2735289
- GTPL10517
- HMS544M04
- DTXSID00370659
- REGID_for_CID_2735289
- HMS2787I06
- ZINC152719
- EX-A4302
- MFCD00052647
- NSC823659
- s9719
- SBB099607
- AKOS000264357
- CCG-233915
- DB15279
- NSC-823659
- PS-7558
- 5-Amino-2-(4-tertbutylphenoxy)pyridine
- [6-(4-tert-butylphenoxy)-3-pyridyl]amine
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