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CLEMIZOLE
SynDRA canonical compound SYN0025215 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | HCV inhibitor |
|---|
| Indication | allergic rhinitis |
|---|
| Disease area | allergy |
|---|
All known targets
- TRPC3
- TRPC4
- TRPC5
- TRPC6
- HCV NS4B
- HRH4
- Hmox2
- Trpc4
- Trpc5
- Trpc7
Mechanisms of action (all sources)
- TRPC3 MODULATOR
- TRPC4 MODULATOR
- TRPC5 MODULATOR
- TRPC6 MODULATOR
- HCV inhibitor
- HCV NS4B MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH1
- PGR
- HTR2B
- NR1I2
- KCNH2
- ABCB11
- LMNA
- MLNR
- MC3R
- MAPT
- MAOA
- HTR3A
- KDR
- HTR2C
- HTR2A
- HTR1A
- HRH3
- HIF1A
- NPSR1
- NR3C1
- ACHE
- OPRD1
- TSHR
- TDP1
- TBXA2R
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SAMHD1
- PTGS2
- PPARG
- PMP22
- PKM
- PDE4D
- PDE3A
- OPRM1
- HDAC6
- GMNN
- GHSR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- HSPB1
- PRGR
- NSD2
- NF2L2
- MDR1
- KSYK
- JUN
- ESRRA
- ACM1
- ESR2
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CP1A2
- SYK
Cross-references
Synonyms
- lergopenin
- clemizole hydrochloride
- clemizole HCl
- Clemizol
- AL-20 FREE BASE
- NSC-46261
- Histacur
- Histakool
- Lergopenin
- Clemizolum
- Depocural
- 1-(p-Chlorobenzyl)-2-pyrrolidylmethylenebenzimidazole
- 1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzo[d]imidazole
- NSC 46261
- UNII-T97CB3796L
- CHEBI:52140
- CJXAEXPPLWQRFR-UHFFFAOYSA-N
- T97CB3796L
- 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole
- 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-
- 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole
- Clemizolo
- Benzimidazole, 1-(p-chlorobenzyl)-2-(1-pyrrolidinylmethyl)-
- NSC46261
- RefChem:918812
- DTXCID8026939
- C19H20ClN3
- 1-p-Chlorobenzyl-2-(1-pyrrolidinylmethyl)benzimidazole
- MFCD00051434
- Clemizolo [DCIT]
- Clemizole [INN:BAN]
- NCGC00015243-02
- Clemizol [INN-Spanish]
- Clemizolum [INN-Latin]
- CAS-1163-36-6
- EINECS 207-133-5
- Clemizole (free base)
- CLEMIZOLE [INN]
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