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MOLSIDOMINE
SynDRA canonical compound SYN0025015 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | GUCY1A3 |
|---|
| Mechanism of action | guanylate cyclase stimulant |
|---|
| Indication | coronary artery disease (CAD) |
|---|
| Disease area | cardiology |
|---|
All known targets
- ESR1
- GUCY1A1
- GUCY1B1
- GUCY1A2
- GUCY1B2
- NPR1
- EGFR
Mechanisms of action (all sources)
- guanylate cyclase stimulant
- Nitric oxide stimulant
- GUCY1B1 ACTIVATOR
- GUCY1A2 ACTIVATOR
- GUCY1A1 ACTIVATOR
- EGFR ACTIVATOR
- GUCY1B2 ACTIVATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- ADORA2A
- NR1I2
- NPY1R
- NPSR1
- MLNR
- MC3R
- LMNA
- KCNH2
- KAT2A
- IDH1
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- NR3C1
- OPRD1
- OPRK1
- SLC6A3
- TDP1
- TBXA2R
- SMAD3
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A2
- OPRM1
- SLC29A1
- SAMHD1
- PTGS2
- PGR
- PDE4D
- PDE3A
- HRH2
- HRH1
- HIF1A
- AGTR1
- CBX1
Drug classes
- Cardiovascular Agents
- Nitric Oxide Donors
- Vasodilator Agents
- Nitrate Vasodilator
- Explosive Agents
- Anti-Asthmatic Agents
- Antioxidants
- Bronchodilator Agents
- Endothelium-Dependent Relaxing Factors
- Free Radical Scavengers
- Gasotransmitters
- Neurotransmitter Agents
ATC classes
- C01D · VASODILATORS USED IN CARDIAC DISEASES
- R07A · OTHER RESPIRATORY SYSTEM PRODUCTS
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Cross-references
Synonyms
- molsidolat
- morsydomine
- motazomin
- molsidomin
- Molsidomina
- Morsydomine
- CAS-276
- CAS276
- NSC-757398
- Corvasal
- Corvaton mite
- Corvaton ret
- Corvaton
- Molsidolat
- Motazomin
- SIN-10
- Sydnopharm
- Morial
- N-Ethoxycarbonyl-3-morpholinosydnonimine
- Molsidominum [INN-Latin]
- Molsidomina [INN-Spanish]
- Molsidomin
- MLS000028573
- UNII-D46583G77X
- CAS 276
- EINECS 247-207-4
- BRN 3999414
- SMR000058990
- Sydnone imine, N-(ethoxycarbonyl)-3-(4-morpholinyl)-
- N-Carboxy-3-morpholinosydnonimine ethyl ester
- N-Carboxy-3-morpholinosydnone imine ethyl ester
- N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine
- Coruno
- Sydnone imine, N-carboxy-3-m
- MFCD00869301
- SIN-10;Morsydomine
- Cholesta-5,8-dien-3ss-ol
- Molsidomine CRS
Reported adverse events
- Headache
- Vertigo
- Hypotension
- Syncope
- Palpitations
- Vomiting
- Nausea
- Tinnitus
- Abdominal discomfort
- Amblyopia
- Asthenia
- Chromaturia
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