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THEOFIBRATE
SynDRA canonical compound SYN0024975 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PPARA |
|---|
| Mechanism of action | Lipase clearing factor inhibitor |
|---|
| Indication | hyperlipidemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
- Platelet aggregation inhibitor
- Lipase clearing factor inhibitor
- PPAR receptor agonist
- PPARA AGONIST
- Peroxisome proliferator-activated receptor alpha agonist
- LPL ACTIVATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ADORA1
- NR3C1
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- OPRD1
- HRH2
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- TDP1
- HRH3
- HRH1
- ADORA2A
- CCKAR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Peripheral Nervous System Agents
- Respiratory System Agents
- Antimetabolites
- Antioxidants
- Hypolipidemic Agents
- Lipid Regulating Agents
- Protective Agents
- Radiation-Sensitizing Agents
- Anticholesteremic Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
Cross-references
Synonyms
- etofylline clofibrate
- ethophylline clofibrate
- etophylline clofibrate
- Etofylline clofibrate
- Clofibrate d'etofylline
- Clofibrato de etofilina
- Clofibrate etofylline
- ML-1024
- NSC-234348
- Duolip
- etofylline-clofibrate
- etofylline.clofibrate
- Etofyllinclofibrate
- Theofibrate [USAN]
- NSC 234348
- 14UH1JQP6L
- Etofylline clofibrate [INN]
- MLS003115174
- 2-(p-Chlorophenoxy)-2-methylpropionic acid, ester with 7-(2-hydroxyethyl)theophylline
- Theofibrate (USAN)
- Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester
- Propionic acid, 2-(4-chlorophenoxy)-2-methyl-, 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl) ethyl ester
- NCGC00160455-01
- Etofylline clofibrate (INN)
- Etofyllinclofibrat
- Etofyllinclofibrat [German]
- Etofyllini clofibras
- SMR001830757
- Etofyllini clofibras [INN-Latin]
- EINECS 259-191-6
- Clofibrate d'etofylline [INN-French]
- UNII-14UH1JQP6L
- Clofibrato de etofilina [INN-Spanish]
- BRN 1233286
- Etofilline clofibrate
- Duolip (TN)
- 1-(7-Theophyllinyl)-2-ethyl (2-(p-chlorophenoxy)isobutyrate)
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