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LETERMOVIR
SynDRA canonical compound SYN0024474 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Mechanism of action | CMV terminase inhibitor |
|---|
| Indication | cytomegalovirus (CMV) |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
- CMV terminase INHIBITOR
- CMV TRM1 INHIBITOR
- TRM1 INHIBITOR
- TRM2 inhibitor
- TRM3 inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- HTR2A
- ADRA1A
- CCKAR
- OPRD1
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- KDR
- MAOA
- MC3R
- MLNR
- NR1I2
- NR3C1
- ABCB11
- HRH3
- PDE3A
- PDE4D
- PGR
- PPARG
- PTGS2
- SCN5A
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- OPRM1
- HDAC6
- HRH1
- ACHE
- ADORA1
- ADORA2A
- ADORA3
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Infective Agents
- Antineoplastic Agents
- Antiviral Agents
- Enzyme Inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 2C19 Inducers
- Cytochrome P450 2C8 Inhibitors
- Organic Anion Transporting Polypeptide 1B1 Inhibitors
- Organic Anion Transporting Polypeptide 1B3 Inhibitors
- Cytochrome P450 3A Inhibitors
- Cytomegalovirus DNA Terminase Complex Inhibitor
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- PREVYMIS
- Prevymis
- prevymis
- AIC246
- AIC-246
- MK-8228
- AIC 246
- 1H09Y5WO1F
- letermovirum
- RefChem:57199
- DTXCID90161174
- J05AX18
- MFCD22572725
- Letermovir [INN]
- Letermovir [USAN:INN]
- UNII-1H09Y5WO1F
- Prevymis (TN)
- Letermovir (Standard)
- Letermovir(AIC246)
- LETERMOVIR [MI]
- LETERMOVIR [JAN]
- LETERMOVIR [USAN]
- Letermovir(AIC-246)?
- LETERMOVIR [WHO-DD]
- Letermovir (JAN/USAN/INN)
- SCHEMBL379403
- orb1301825
- LETERMOVIR [ORANGE BOOK]
- SCHEMBL29367234
- SCHEMBL29438348
- C29H28F4N4O4
- EX-A1871
- BDBM50614677
- EBC-27337
- HY-15233R
- s8873
- AKOS030526995
- CS-1571
Reported adverse events
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