← SynDRA

HISPIDIN

SynDRA canonical compound SYN0024035 — structure-anchored drug synonym record

All known targets

• PRKCB

Mechanisms of action (all sources)

• PKC inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ALDH1A1
• NFE2L2
• TSG101
• TDP1
• SMN1
• RGS4
• RECQL
• POLK
• POLI
• POLH
• POLB
• PMP22
• PIN1
• MPHOSPH8
• APEX1
• MBNL1
• MAPT
• LMNA
• KDM4E
• HSPA5
• HPGD
• FEN1
• EHMT2
• CBX1
• BLM
• ARSA
• VDR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ALAT2
• COMT
• DPOLB
• EZH2
• GAMT
• GLSK
• GNMT
• HNMT
• HS90A
• HS90B
• MITF
• NNMT
• NTM1A
• PNMT

Cross-references

• PubChem CID: 54685921
• ChEMBL: CHEMBL1224512
• ChEBI: 36332
• Wikipedia: Hispidin
• LINCS BRD: BRD-K07325606

Synonyms

• 6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone
• SSJ18CG55E
• CHEBI:36332
• 6-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxypyran-2-one
• 6-((E)-2-(3,4-dihydroxyphenyl)ethenyl)-4-hydroxypyran-2-one
• RefChem:146558
• DTXCID001475448
• Isohispidine
• Hispidine
• (E)-6-(3,4-dihydroxystyryl)-4-hydroxy-2H-pyran-2-one
• 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone
• MFCD22199534
• 2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxypyran-4-one
• 6-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-4-hydroxy-pyran-2-one
• UNII-SSJ18CG55E
• 2-((E)-2-(3,4-DIHYDROXYPHENYL)ETHENYL)-6-HYDROXYPYRAN-4-ONE
• Lopac0_000634
• SCHEMBL246649
• orb1299502
• SCHEMBL12305090
• CHEBI:131178
• CHEBI:204209
• HMS3261P10
• 2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxy-4-pyranone
• AAA55555
• EX-A4157
• Tox21_500634
• BDBM50498538
• Hispidin, solid, >=98% (HPLC)
• HSCI1_000157
• AKOS015896249
• AKOS030537191
• CCG-204722
• EBC-512281
• LP00634
• SDCCGSBI-0050615.P002
• SMP2_000346