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PRUVANSERIN
SynDRA canonical compound SYN0023922 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | HTR2A | HTR2C |
|---|
| Mechanism of action | serotonin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- serotonin receptor antagonist
- HTR2A MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TMEM97
- SLC6A4
- SLC6A2
- SIGMAR1
- ADRB2
- HTR1D
- HTR2B
- DRD4
- HTR7
- ADGRF1
- HTR5A
- HRH4
- HTR1A
- HTR1B
- HTR1E
- HTR3A
- NEIL2
- HTR6
- MPG
- HRH2
- NTHL1
- OGG1
- OPRK1
- S1PR1
- SLC6A3
- SMUG1
- HRH3
- HDAC6
- HRH1
- CHRM1
- ADRA1B
- ADRA1D
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB3
- AGTR1
- APLNR
- C5AR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Pruvanserine
- Pruvanserina
- LY2422347
- EMD-390920
- EMD-281014
- EMD390920
- LSN-2422347
- LSN2422347
- LY-2420586
- LY-2422347
- LY-2422347 FREE BASE
- LY2420586
- UNII-UL09X1D9EM
- UL09X1D9EM
- CHEMBL1215661
- Pruvanserin [USAN:INN]
- 7-{4-(2-(4-Fluorophenyl)ethyl)piperazine-1-carbonyl}-1H-indole-3-carbonitrile
- 7-[4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl]-1H-indole-3-carbonitrile
- AC1O5FMC
- Pruvanserin (USAN/INN)
- SCHEMBL678751
- DTXSID40196133
- AQRLDDAFYYAIJP-UHFFFAOYSA-N
- ZINC56898757
- BDBM50324540
- SB16534
- DB13094
- NCGC00370956-01
- D06632
- L001679
- EMD 390920
- LY 2422347
- pruvanserinum
- RefChem:1097077
- DTXCID50118624
- Pruvanserin [INN]
- PRUVANSERIN [USAN]
- orb2564346
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