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DEFLAZACORT
SynDRA canonical compound SYN0023631 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | NR3C1 |
| Mechanism of action | Glucocorticoid receptor agonist |
| Indication | joint inflammation |
| Disease area | rheumatology |
All known targets
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ESR1
- PGR
- NPY1R
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MAOB
- MC3R
- MLNR
- ADORA1
- HRH2
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HRH3
- HRH1
- ADORA2A
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- JUN
- NSD2
- PRGR
- RARA
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Immunologic Factors
- Immunosuppressive Agents
ATC classes
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Cross-references
Synonyms
- EMFLAZA
- Emflaza
- JAYTHARI
- Jaythari
- PYQUVI
- Pyquvi
- azacort
- azacortinol
- calcort
- dezacor
- dezacort
- flantadin
- lantadin
- oxazacort
- Azacortinol
- DL-458IT
- L-5458
- MDL-458
- MDL458
- Calcort
- Zamene
- C25H33NO6
- Deflazacort (Calcort)
- Deflazacortum [INN-Latin]
- EINECS 238-483-7
- Deflan (TN)
- AC1L1BQ2
- Deflazacort [USAN:BAN:INN]
- CTK8F9001
- MolPort-035-394-927
- Azacort
- Oxazacort
- Flantadin
- Cortax
- Deflan
- KR5YZ6AE4B
- Dezacor
Reported adverse events
- Abdominal discomfort
- Acne
- Anxiety
- Back injury
- Back pain
- Chromaturia
- Cough
- Cushingoid
- Dizziness
- Dyspepsia
- Erythema
- Glucose urine present
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