← SynDRA
CARGLUMIC ACID
SynDRA canonical compound SYN0023620 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CPS1 |
|---|
| Mechanism of action | Carbamoyl phosphate synthase activator |
|---|
| Indication | hyperammonemia |
|---|
| Disease area | metabolism |
|---|
All known targets
Mechanisms of action (all sources)
- Carbamoyl phosphate synthase activator
- CPS1 POSITIVE ALLOSTERIC MODULATOR
- Carbamoyl-phosphate synthase [ammonia], mitochondrial positive allosteric modulator
- CPS1 ACTIVATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- HRH3
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4A
- PDE4D
- PGR
- PTGS1
- SLC6A2
- SLC6A3
- SLC6A4
- HTR1A
- HRH2
- ADORA1
- HRH1
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB2
- AR
- CHRM1
- CHRM2
- CHRM3
- CNR1
- DRD1
- DRD2
- DRD3
- ESR1
- F2
- GALC
- HDAC6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Carbamoyl Phosphate Synthetase 1 Activators
- Carbamoyl Phosphate Synthetase 1 Activator
ATC classes
- A16A · OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Cross-references
Synonyms
- CARBAGLU
- Carbaglu
- carbaglu
- (2S)-2-(carbamoylamino) pentanedioic acid
- Acide carglumique
- Acido carglumico
- N-carbamyl-l-glutamic acid
- NSC-760124
- OE-312
- OE 312 (LABORATORY CODE DESIGNATION)
- Ucedane
- Carbaglu (TN)
- carglumic-acid
- OE 312
- N-Carbamylglutamate
- N-Carbamoyl-L-glutamic acid
- N-Carbamyl-L-glutamic acid
- carglumic acid (usp-rs)
- NSC 760124
- CARBAMYL-L-GLUTAMIC ACID
- 5L0HB4V1EW
- L-Glutamic acid, N-(aminocarbonyl)-
- (2S)-2-(carbamoylamino)pentanedioic acid
- Ureidoglutaric acid
- Carbamylglutamic acid
- Carbamino-L-glutamic acid
- L-N-Carbamoylglutamic acid
- acido carglumico
- acide carglumique
- acidum carglumicum
- DTXCID5026706
- CHEBI:71028
- CarglumicAcid
- RefChem:57054
- (S)-2-ureidopentanedioic acid
- N-Carbamyl-L-glutamate
Reported adverse events
- Abdominal pain
- Asthenia
- Dysgeusia
- Ear infection
- Headache
- Hyperhidrosis
- Infection
- Influenza
- Nasopharyngitis
- Pneumonia
- Pyrexia
- Rash
Look up CARGLUMIC ACID in the interactive SynDRA portal →