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PRASUGREL
SynDRA canonical compound SYN0023614 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | P2RY12 |
|---|
| Mechanism of action | Purinergic receptor antagonist |
|---|
| Indication | acute coronary syndrome (ACS) | myocardial infarction |
|---|
| Disease area | cardiology |
|---|
All known targets
- P2RY12
- CYP2B6
- CYP2C19
- CYP3A5
Mechanisms of action (all sources)
- Purinergic receptor antagonist
- P2RY12 ANTAGONIST
- Purinergic receptor P2Y12 antagonist
- P2RY12 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- AR
- HTR1A
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- HTR2B
- HRH3
- ACHE
- HDAC6
- F2
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- ADRA2A
- ADRA1A
- ADORA3
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2C9
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- GCR
- GPX1
- NR1I2
- RARA
Drug classes
- Hematologic Agents
- Platelet Aggregation Inhibitors
- P2Y12 Platelet Inhibitor
- P2Y12 Receptor Antagonists
ATC classes
- B01A · ANTITHROMBOTIC AGENTS
Cross-references
Synonyms
- EFFIENT
- Effient
- PRASUGREL HYDROCHLORIDE
- prasugrel hydrochloride
- effient
- efient
- prasugrel HCl
- CS-747
- LY640315
- LY-640315
- NSC-759625
- Efient
- Effient (TN)
- LY 640315
- NSC 759625
- CS 747
- CHEBI:87723
- HSDB 7995
- prasugrelum
- RefChem:56600
- CHEBI:87715
- B01AC22
- DTXCID70197355
- Prasugrel (Effient)
- C20H20FNO3S
- MFCD09954140
- Pcr 4099
- Prasita
- Prasugrel [INN]
- SMR002533665
- UNII-34K66TBT99
- Prasugrel [INN:BAN]
- NCGC00188690-01
- NCGC00188690-02
- Prasugrel?
- Prasugrel-[d5]
- Prasugrel (Standard)
Reported adverse events
- NGS
- Hypersensitivity
- Rash
- Back pain
- Dizziness
- Headache
- Nausea
- Pyrexia
- Thrombotic thrombocytopenic purpura
- Atrial fibrillation
- Bradycardia
- Cough
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