← SynDRA

RUFINAMIDE

SynDRA canonical compound SYN0023605 — structure-anchored drug synonym record

All known targets

• SCN1A
• SCN3A
• SCN9A
• SCN10A
• SCN11A
• SCN2A
• SCN4A
• SCN5A
• SCN7A
• SCN8A
• CA5A
• CYP2E1

Mechanisms of action (all sources)

• Voltage-gated sodium channel blocker
• SCN1A BLOCKER
• Sodium channel alpha subunit blocker
• SCN5A BLOCKER
• SCN4A BLOCKER
• SCN7A BLOCKER
• SCN2A BLOCKER
• SCN9A BLOCKER
• SCN3A BLOCKER
• SCN11A BLOCKER
• SCN8A BLOCKER
• SCN10A BLOCKER

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ADORA1
• NR1I2
• HRH1
• HRH2
• HRH3
• HTR1A
• HTR2A
• HTR2B
• KCNH2
• MAOA
• MC3R
• MLNR
• NPY1R
• NR3C1
• GHSR
• OPRM1
• PDE3A
• PDE4D
• PGR
• PPARG
• PTGS2
• SLC29A1
• SLC6A2
• SLC6A3
• SLC6A4
• SMAD3
• HDAC6
• ESR1
• ADORA2A
• BDKRB2
• ADORA3
• ADRA1A
• ADRA2A
• ADRA2C
• ADRB1
• ADRB2
• AGTR1
• APEX1
• ARSA
• AVPR1A

Drug classes

• Anticonvulsants
• Cardiovascular Agents
• Central Nervous System Agents
• Membrane Transport Modulators
• Sodium Channel Blockers
• Voltage-Gated Sodium Channel Blockers

ATC classes

• N03A · ANTIEPILEPTICS

Cross-references

• PubChem CID: 129228
• ChEMBL: CHEMBL1201754
• DrugBank: DB06201
• ChEBI: CHEBI:134966
• KEGG: D05775
• RxNorm: 69036
• Wikipedia: Rufinamide
• TTD: D0MD2L
• LINCS BRD: BRD-K20079257

Synonyms

• BANZEL
• Banzel
• inovelon
• banzel
• CGP 33101
• Rufinamida
• 60231/4
• CGP-33101
• E-2080
• E2080
• RUF-331
• Inovelon
• Cgp 33101
• Xilep
• RUF 331
• UNII-WFW942PR79
• WFW942PR79
• C10H8F2N4O
• POGQSBRIGCQNEG-UHFFFAOYSA-N
• NCGC00165883-02
• DSSTox_CID_26506
• DSSTox_RID_81675
• DSSTox_GSID_46506
• Banzel, Rufinamide
• SYN-111
• Rufinamide (USAN/INN)
• Inovelon/Banzel
• E 2080
• rufinamide (usp monograph)
• rufinamide (usp-rs)
• DTXCID9026506
• rufinamidum
• RefChem:57756
• SYN11
• N03AF03
• MFCD00865314
• s1256

Reported adverse events

• Constipation
• Diplopia
• Dizziness
• Fatigue
• Headache
• Hypersensitivity
• Nausea
• Rash
• Somnolence
• Vomiting
• Aggression
• Anxiety