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IXABEPILONE
SynDRA canonical compound SYN0023603 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TUBB |
|---|
| Mechanism of action | microtubule stabilizing agent |
|---|
| Indication | breast cancer |
|---|
| Disease area | oncology |
|---|
All known targets
- TUBB
- TUBB1
- TUBB2A
- TUBB2B
- TUBB3
- TUBB4A
- TUBB4B
- TUBB6
- TUBB8
- BCL2
- TUBA1A
- TUBA1B
Mechanisms of action (all sources)
- TUBB4B INHIBITOR
- TUBB1 INHIBITOR
- TUBA3C INHIBITOR
- TUBA4A INHIBITOR
- TUBB3 INHIBITOR
- TUBA1A INHIBITOR
- TUBB4A INHIBITOR
- TUBB8 INHIBITOR
- TUBB INHIBITOR
- TUBA1B INHIBITOR
- TUBA1C INHIBITOR
- TUBA3E INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
ATC classes
- L01D · CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
Cross-references
Synonyms
- IXEMPRA
- IXEMPRA KIT
- Azaepothilone B
- ixempra
- BMS-247550
- Ixabepilona
- Azaepothilone b
- Ixempra
- BMS-247550-01
- NSC-747973
- Ixempra kit
- Ixempra (TN)
- BMS 247550
- Aza-epothilone B
- BMS 247550-1
- NSC 747973
- CHEBI:63605
- K27005NP0A
- NSC747973
- Ixabepilone [INN]
- Ixempra (TM)
- 16-Aza-epothilone B
- IXABEPILONE [MI]
- IXABEPILONE [JAN]
- IXABEPILONE [HSDB]
- IXABEPILONE [USAN]
- IXABEPILONE [VANDF]
- SCHEMBL8386
- IXABEPILONE [MART.]
- IXABEPILONE [USP-RS]
- IXABEPILONE [WHO-DD]
- UNII-K27005NP0A
- Ixabepilone (JAN/USAN/INN)
- Ixabepilone [USAN:INN:JAN]
- GTPL6824
- SCHEMBL1890345
- Ixabepilone (BMS-247550)
- CHEMBL1201752
Reported adverse events
- Abdominal pain
- Alopecia
- Chest pain
- Constipation
- Cough
- Dehydration
- Dizziness
- Fatigue
- Febrile neutropenia
- Headache
- Hypersensitivity
- Infection
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