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LOVASTATIN ACID
SynDRA canonical compound SYN0023566 — structure-anchored drug synonym record
| Primary target(s) | HMGCR |
|---|
| Mechanism of action | HMGCR inhibitor |
|---|
All known targets
- HMGCR
- CYP3A5
- HDAC2
- ITGAL
- NR1I2
- SLC6A2
- SLC6A3
- ADORA1
- HCAR2
- HCAR3
- HDAC1
- HDAC6
Mechanisms of action (all sources)
- HMGCR INHIBITOR
- HMG-CoA reductase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HMGCR
- SLCO1B1
- ABCB1
- ABCC2
Drug classes
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- HMG-CoA Reductase Inhibitor
- Anticholesteremic Agents
- Antimetabolites
- Enzyme Inhibitors
- Hypolipidemic Agents
- Lipid Regulating Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- Hydroxyacid lovastatin
- Mevinolinic acid
- MK-819
- MSD-803 ACID
- Monacolinic K acid
- L 154819
- 5CLV35Y90C
- CHEBI:82985
- lovestatin acid
- RefChem:818793
- DTXCID70820838
- L-154,819
- MSD 803 free acid
- LVA
- UNII-5CLV35Y90C
- orb1987154
- SCHEMBL1977672
- BDBM50406681
- EX-A10840
- AKOS040746108
- HY-122439
- HYDROXYACID LOVASTATIN [EP IMPURITY]
- LOVASTATIN IMPURITY B [EP IMPURITY]
- CS-0085508
- NS00069831
- C21130
- T24461
- Lovastatin hydroxy acid observed in lovastatin standard
- (3r,5r)-7-((1r,2r,6s,8r,8as)-2,6-Dimethyl-8-{[(2r)-2-Methylbutanoyl]Oxy}-1,2,6,7,8,8a-Hexahydronaphthalen-1-Yl)-3,5-Dihydroxyheptanoic Acid
- L-154819
- MK 819
- MSD 803 acid
- orb3025391
- Lovastatin hydroxy acid sodium salt
- HY-123672
- UNII-LK08RY63S3
- Sodium mevinolinate
- T19918
Reported adverse events
- Asthenia
- Constipation
- Dizziness
- Dyspepsia
- Flatulence
- Headache
- Hypersensitivity
- Myalgia
- Myopathy
- Nausea
- Rash
- Rhabdomyolysis
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