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GLYCOPYRRONIUM
SynDRA canonical compound SYN0023542 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | CHRM3 |
| Mechanism of action | Acetylcholine receptor antagonist |
| Indication | peptic ulcer disease (PUD) |
| Disease area | gastroenterology |
All known targets
- CHRM1
- CHRM3
- CHRM2
- CHRM4
- CHRM5
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- CHRM3 INHIBITOR
- CHRM4 INHIBITOR
- CHRM1 INHIBITOR
- CHRM2 INHIBITOR
- CHRM5 INHIBITOR
- CHRM2 ANTAGONIST
- CHRM4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- HTR2B
- ACHE
- PDE4A
- HTR3A
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS1
- PTGS2
- SAMHD1
- SLC22A1
- SLC22A2
- SLC29A1
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR2C
- HTR2A
- ADORA1
- BDKRB2
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cholinergic Antagonists
- Anticholinergic
- Adjuvants, Anesthesia
- Central Nervous System Agents
- Cholinergic Agents
- Muscarinic Antagonists
- Neurotransmitter Agents
ATC classes
- A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- R03B · OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
- D11A · OTHER DERMATOLOGICAL PREPARATIONS
- ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
- ADRENERGICS, INHALANTS
Cross-references
Synonyms
- BEVESPI AEROSPHERE
- BREZTRI AEROSPHERE
- CUVPOSA
- Cuvposa
- DARTISLA ODT
- GLYCOPYRROLATE
- GLYCOPYRRONIUM TOSYLATE
- GLYRX-PF
- Glycate
- LONHALA MAGNAIR KIT
- PREVDUO
- QBREXZA
- glycopyrronium bromide
- sialanar
- NVA237
- Seebri Breezhaler
- copyrrolate
- gastrodyn
- glycopyrrolate
- robanul
- glycopyrrolate bromide
- glycopyrronium tosilate
- glycopyrronium tosilate hydrate
- Glycopyrrolate cation
- Glycopyrrolate ion
- Glycopyrronium cation
- Glycopyrronium ion
- Glycopyrronium, erythro-
- A14FB57V1D
- RefChem:922362
- Robinal
- NCGC00179456-02
- Tovanor Breezhaler
- Prestwick0_000746
- Prestwick1_000746
- Prestwick2_000746
- Prestwick3_000746
- BSPBio_000732
Reported adverse events
- Injection site reaction
- Headache
- Sinusitis
- Constipation
- Pneumonia
- Vomiting
- Agitation
- Flushing
- Dry skin
- Irritability
- Dehydration
- Heart rate
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