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DEXAMETHASONE PHOSPHORIC ACID
SynDRA canonical compound SYN0023524 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
| Indication | acute respiratory distress syndrome |
|---|
| Disease area | Lung diseases |
|---|
All known targets
- NR3C1
- AR
- Ar
- Fabp1
- NR3C2
- Nr3c1
- PGR
- ANXA1
- CYP3A4
- CYP3A5
- NOS2
- NR0B1
Mechanisms of action (all sources)
- NR3C1 AGONIST
- ESRRA AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR1
- ACHE
- KCNH2
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PDE4A
- PDE3A
- OPRM1
- NFE2L2
- MBNL1
- MAOA
- KDR
- HTR2B
- ADORA3
- HTR1A
- HRH3
- HIF1A
- HDAC6
- GMNN
- F2
- EHMT2
- DRD3
- DRD1
- CHRM2
- CHRM1
- ADRA2A
- ADRA1A
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Glucocorticoids
- Hormones
- Anti-Inflammatory Agents
- Antiemetics
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Central Nervous System Agents
- Gastrointestinal Agents
- Peripheral Nervous System Agents
- Anti-Allergic Agents
ATC classes
- A01A · STOMATOLOGICAL PREPARATIONS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- S02B · CORTICOSTEROIDS
- D07A · CORTICOSTEROIDS, PLAIN
- D10A · ANTI-ACNE PREPARATIONS FOR TOPICAL USE
- S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- S01B · ANTIINFLAMMATORY AGENTS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
- CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION
Cross-references
Synonyms
- DECADRON
- DECADRON W/ XYLOCAINE
- DEXACEN-4
- DEXACORT
- DEXAIR
- DEXAMETHASONE
- DEXAMETHASONE SODIUM PHOSPHATE
- DEXAMETHASONE SODIUM PHOSPHATE PRESERVATIVE FREE
- HEXADROL
- MAXIDEX
- NEODECADRON
- NEOMYCIN SULFATE AND DEXAMETHASONE SODIUM PHOSPHATE
- dexamethasone phosphate
- dexamethasone sodium phosphate
- decadron
- Dexamethasone phosphate
- Dexamethasone sodium phosphate
- EryDex
- Dexamethasone sodium phosphate (erythrocyte encapsulated)
- Dexamethasone sodium phosphate (erythrocyte encapsulated), Urbino University/EryDel
- Dex 21-P (red blood cell encapsulated), Urbino University/EryDel
- Intra-erythrocyte dexamethasone (inflammatory diseases), Urbino University/EryDel
- Dexamethasone Phosphate
- Dexamethasone-21-phosphate
- Betnelan phosphate
- Hexadrol phosphate
- Dexamethasone 21-orthophosphate
- Dexamethasone-21-dihydrogen-phosphate
- EGP-437
- 2BP70L44PR
- CHEBI:68637
- AL38905
- AL-38905
- RefChem:585854
- DTXCID5031345
- Neodecadron
- Wymesone
- Oradexon phosphate
Reported adverse events
- Exophthalmos
- Bradycardia
- Acne
- Anaphylactoid reaction
- Hypertension
- Sodium retention
- Fluid retention
- Petechiae
- Fungal infection
- Peptic ulcer
- Erythema
- Increased appetite
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