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DIPHENOXYLATE
SynDRA canonical compound SYN0023521 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | OPRM1 |
|---|
| Mechanism of action | Opioid receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- Opioid receptor agonist
- OPRM1 AGONIST
- Mu opioid receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- EHMT2
- GLP1R
- GMNN
- TDP1
- USP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- PRGR
- PPARG
- OPRD
- NSD2
- NR1I2
- NR1H4
- NF2L2
- MDM4
- MDM2
- M4K2
- KCNQ1
- KCNH2
- KCMB2
- KCMB1
- GEMI
- GCR
- ESRRA
- ESR2
- ESR1
- DRD3
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- CAC1H
- TP53
Drug classes
- Analgesics
- Analgesics, Opioid
- Antidiarrheals
- Central Nervous System Agents
- Central Nervous System Depressants
- Gastrointestinal Agents
- Narcotics
- Peripheral Nervous System Agents
- Sensory System Agents
- Antidiarrheal
ATC classes
Cross-references
Synonyms
- COLONAID
- DI-ATRO
- DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE
- DIPHENOXYLATE HYDROCHLORIDE W/ ATROPINE SULFATE
- LO-TROL
- LOGEN
- LOMANATE
- LOMOTIL
- LONOX
- LOW-QUEL
- diphenoxylate hydrochloride
- diphenoxylate HCl
- Difenoxilato
- IDS-ND-016
- Difenossilato
- Diphenoxalate
- Diphenoxylatum
- Difenossilato [DCIT]
- Difenoxilato [Spanish]
- Diphenoxylate HCl
- Diphenoxylate Monohydrochloride
- Diphenoxylate hydrochloride
- Diphenoxylatum [Latin]
- NIH 7562
- R-1132
- Difenoxilato [INN-Spanish]
- Diphenoxylate (INN)
- Diphenoxylate [INN:BAN]
- Diphenoxylate hydrochloride (USP)
- Diphenoxylate hydrochloride(usp)
- Diphenoxylatum [INN-Latin]
- R 1132 (antiperistaltic)
- Co-phenotrope (TN)
- R 1132
- CHEBI:4639
- RefChem:588812
- DTXCID902951
- A07DA01
Reported adverse events
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