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OXYPHENONIUM
SynDRA canonical compound SYN0023514 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CHRM1 |
|---|
| Mechanism of action | Cholinergic receptor antagonist |
|---|
| Indication | peptic ulcer disease (PUD) |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- Cholinergic receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- CHRM4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM2
- ACHE
- SLC22A2
- OPRM1
- PDE3A
- PDE4A
- PGR
- PIN1
- PTGS1
- SLC22A1
- SLC47A1
- MAOA
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- SMAD3
- TBXA2R
- NFE2L2
- KDR
- ADORA3
- ESR1
- ADRA1A
- ADRA2A
- AR
- CBX1
- DRD1
- DRD3
- F2
- KCNH2
- GMNN
- HDAC6
- HRH3
- HTR1A
- HTR2B
- IDH1
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM4
- ACM5
- ANDR
- CFTR
- CP2D6
- CP3A4
- IL1B
- KCMA1
- KCMB2
Drug classes
- Mydriatics
- Cholinergic Agents
- Cholinergic Antagonists
- Muscarinic Antagonists
- Neurotransmitter Agents
- Parasympatholytics
- Peripheral Nervous System Agents
ATC classes
- A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Cross-references
Synonyms
- ANTRENYL
- antrenyl
- oxyphenonium bromide
- Oxyphenonium cation
- Oxyphenonium ion
- Argicillin
- Atrenyl
- Hydroxymethylgramicidin
- Methacin
- Methocidin
- Methocidine
- Methocidinum
- Metocidina
- Oxiphenonum
- Spastrex;Oxyphenonium Chloride
- Oxyphenonium Iodide
- Methocidin [DCF:INN]
- Methocidine [INN-French]
- Methocidinum [INN-Latin]
- Metocidina [INN-Spanish]
- 2-((Cyclohexylhydroxyphenylacetyl)oxy)-N,N-diethyl-N-methylethanaminium
- 2-[2-cyclohexyl(hydroxy)phenylacetoxy]-n,n-diethyl-n-methylethanaminium
- D2G5508Y7I
- Iodide, Oxyphenonium
- Chloride, Oxyphenonium
- RefChem:169070
- DTXCID9028203
- Metacin
- NCGC00018256-02
- UNII-D2G5508Y7I
- OXYPHENONIUM [VANDF]
- OXYPHENONIUM [WHO-DD]
- SCHEMBL250614
- GTPL7257
- orb2814790
- CHEBI:94329
- GFRUPHOKLBPHTQ-UHFFFAOYSA-N
- STL325089
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