← SynDRA
BUCLIZINE
SynDRA canonical compound SYN0023508 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | histamine receptor antagonist |
|---|
| Indication | migraine headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- histamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- CNR1
- OPRK1
- ADORA1
- NR3C1
- HTR2C
- HTR3A
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- OPRD1
- HTR2A
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR2B
- HTR1A
- ADORA2A
- BDKRB2
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- CCKAR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Histamine Agents
- Histamine Antagonists
- Neurotransmitter Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- BUCLADIN-S
- buclifen
- histabuticine
- histabutizine
- histabutyzine
- hitabutyzyne
- buclizine hydrochloride
- buclizine HCl
- Buclizina
- Bucladin
- Buclifen
- Buclina
- Buclizinum
- Buclodin
- Histabuticine
- Histabutizine
- Histabutyzine
- Hitabutyzyne
- Posdel
- Softran
- Vibazine
- Aphilan R
- Buclizine dihydrochloride
- Buclizine hydrochloride
- Component of Softran
- Histabutyzine dihydrochloride
- Histabutyzine hydrochloride
- Vibazine hydrochloride
- AH 2526
- UCB 4445
- Aphilan-R base
- Buclina (TN)
- Buclizina [INN-Spanish]
- Buclizine (INN)
- Buclizine [INN:BAN]
- Buclizine, hydrochloride
- Buclizinum [INN-Latin]
- Component of Bucladin-S
Look up BUCLIZINE in the interactive SynDRA portal →