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LEVOBUNOLOL
SynDRA canonical compound SYN0023489 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ADRB2 |
|---|
| Mechanism of action | Adrenergic receptor antagonist |
|---|
| Indication | glaucoma | ocular hypertension |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- ADRB1
- ADRB2
- ADRB3
- Adrb3
- HTR1A
- Htr1a
- SIGMAR1
- SLC6A4
Mechanisms of action (all sources)
- Adrenergic receptor antagonist
- ADRB1 ANTAGONIST
- Beta-1 adrenergic receptor antagonist
- ADRB2 ANTAGONIST
- Beta-2 adrenergic receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- NPY2R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- NPY1R
- NR3C1
- GMNN
- OPRD1
- VDR
- TSHR
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A3
- SLC6A2
- SAMHD1
- PTPRC
- PTGS2
- PTGS1
- PTAFR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic beta-Antagonists
- beta-Adrenergic Blocker
- Adrenergic Agents
- Adrenergic Antagonists
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sympatholytics
ATC classes
- S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Cross-references
Synonyms
- AKBETA
- BETAGAN
- Betagan
- LEVOBUNOLOL HYDROCHLORIDE
- levobunolol hydrochloride
- levobunolol HCl
- betagan
- Bunolol, (-)-
- Bunolol, (s)-
- Akbeta
- Levobunololum
- Levobunolol HCl
- Betegan (TN)
- Levobunolol (INN)
- Levobunolol [INN:BAN]
- Levobunololum [INN-Latin]
- Liquifilm (TN)
- W-6412A
- W-7000A
- AK-Beta (TN)
- (-)-Bunolol
- CHEBI:6438
- G6317AOI7K
- LEVOBUNOLOL [INN]
- l-Bunolol
- CCRIS 4375
- NCGC00016801-01
- CAS-27912-14-7
- liquifilm
- UNII-G6317AOI7K
- (-)-Levobunolol hydrochloride
- beta-site
- Ak-beta
- W-6421A
- BRN 1887243
- LEVOBUNOLOL [MI]
- Prestwick0_000847
Reported adverse events
- Bradycardia
- Bronchospasm
- Depression
- Headache
- Hypersensitivity
- Nausea
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