MEPHENTERMINE

SynDRA canonical compound SYN0023486 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · OTC
Primary target(s)	ADRA1A \| ADRA1B \| ADRA1D \| ADRA2A \| ADRA2B \| ADRA2C \| ADRB1 \| ADRB2 \| ADRB3
Mechanism of action	adrenergic receptor agonist
Indication	hypotension
Disease area	cardiology

All known targets

ADRA1A
ADRA1B
ADRA1D
ADRA2B
ADRA2C
ADRB1
ADRB2
ADRB3
ADRA2A
DRD2
TADA2A

Mechanisms of action (all sources)

ADRA1A AGONIST
Adrenergic receptor agonist
ADRA2A AGONIST
ADRB1 AGONIST
ADRB2 AGONIST
ADRA2C AGONIST
ADRA1D AGONIST
ADRA1B AGONIST
ADRA2B AGONIST
ADRB3 AGONIST
TADA2A AGONIST
DRD2 AGONIST

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

APEX1
CYP1A2
CYP2C19
CYP2C9
CYP2D6
CYP3A4
GMNN
HDAC6
LMNA
SAMHD1
SLCO1B1
SLCO1B3
TARDBP

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

CP2D6

Drug classes

Adrenergic Agents
Adrenergic Agonists
Adrenergic alpha-1 Receptor Agonists
Adrenergic alpha-Agonists
Cardiovascular Agents
Neurotransmitter Agents
Peripheral Nervous System Agents
Sympathomimetics
Vasoconstrictor Agents

ATC classes

C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES

Cross-references

PubChem CID: 3677
ChEMBL: CHEMBL1201234
DrugBank: DB01365
ChEBI: CHEBI:6755
KEGG: D08180
RxNorm: 6756
Wikipedia: Mephentermine
TTD: D0G1OZ
LINCS BRD: BRD-K18194590

Synonyms

Look up MEPHENTERMINE in the interactive SynDRA portal →