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ISOPROPAMIDE
SynDRA canonical compound SYN0023484 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CHRM3 | CHRM4 |
|---|
| Mechanism of action | acetylcholine receptor antagonist |
|---|
| Indication | gastrointestinal acidosis | peptic ulcer disease (PUD) |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- acetylcholine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CHRM2
- KCNH2
- ADORA1
- MC3R
- NR3C1
- NR1I2
- NPY1R
- MLNR
- MC4R
- MAOA
- OPRK1
- LMNA
- KDM4E
- KDM4A
- KAT2A
- HTR3A
- HTR2C
- OPRD1
- OPRM1
- HTR2A
- PDE3A
- PDE4D
- PGR
- PLK1
- POLI
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- HTR2B
- HTR1A
- ADORA2A
- CHRNA4
- ADORA3
- ADRA1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3A
- ACM4
- ACM5
- CP2C9
- CP2D6
- CP3A4
- CP3A7
- CTDS1
- ERAP1
- GNAI1
- IF4H
- NTM1A
- NTMT1
- RGS12
ATC classes
- A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
- ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
Cross-references
Synonyms
- DARBID
- isopropamide bromide
- isopropamid
- isopropamide iodide
- Isopropamide cation
- Isopropamide ion
- Isopropamid
- (3-Carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium
- EINECS 231-316-9
- 8B9I31H724
- BRN 3913368
- ISOPROPAMIDE [VANDF]
- ISOPROPAMIDE [WHO-DD]
- DTXCID203174
- AMMONIUM, (3-CARBAMOYL-3,3-DIPHENYLPROPYL)DIISOPROPYLMETHYL-
- RefChem:792089
- Chloroisopropamide
- 2,2-Diphenyl-4-diisopropylaminobutyramide methiodide
- 4-(Diisopropylamino)-2,2-diphenylbutyramide methiodide
- Priamide Eupharma
- NCGC00016308-01
- CAS-7492-32-2
- SKF 4740
- R-79
- UNII-8B9I31H724
- Isopropamide Iodide
- component of Combid
- Spectrum_000203
- Prestwick0_000770
- Prestwick1_000770
- Prestwick2_000770
- Prestwick3_000770
- Spectrum2_001051
- Spectrum3_000473
- Spectrum4_000023
- Spectrum5_000878
- cid_6284
- BSPBio_000820
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