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DYCLONINE
SynDRA canonical compound SYN0023473 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN10A | SCN5A |
|---|
| Mechanism of action | sodium channel blocker |
|---|
| Indication | local anesthetic |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SCN10A
- SCN5A
- SCN11A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN7A
- SCN8A
- SCN9A
- ACHE
Mechanisms of action (all sources)
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
- sodium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH1
- SLC6A3
- HRH3
- HRH2
- KCNH2
- ESR1
- DRD4
- DRD3
- DRD1
- CHRM2
- SLC6A2
- HTR2A
- ADRB2
- ADRA2C
- ADRA1A
- MAOA
- TACR2
- NFE2L2
- MLNR
- MC4R
- MC3R
- TBXA2R
- MAPT
- LMNA
- SLC6A4
- TDP1
- IDH1
- HTR7
- HTR6
- HTR5A
- THRB
- HTR3A
- NPY1R
- SLCO1B3
- NPY2R
- NR3C1
- SMAD3
- SMN1
- SLC29A1
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- ACM1
- THB
- SYK
- RARA
- NSD2
- NR1I2
- NLRP1
- NF2L2
- MRGPRX1
- KSYK
- HSPB1
- GEMI
- CP3A7
- CP2D6
- CP2C9
- CP1A2
- ANDR
- ALR
- TOR1A
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- R02A · THROAT PREPARATIONS
- N01B · ANESTHETICS, LOCAL
Cross-references
Synonyms
- DYCLONE
- DYCLOPRO
- Dyclopro
- dyclonine hydrochloride
- dyclocaine
- dyclonin
- dyclonine HCl
- Diclonina
- Diclonia
- Dyclocaine
- Dyclocainum
- Dyclonin
- Dycloninum
- Dyclothane
- Tanaclone
- Diclonina [INN-Spanish]
- Dyclonine (INN)
- Dyclonine [INN:BAN]
- Dycloninum [INN-Latin]
- 2-(1-piperidyl)ethyl p-butoxyphenyl ketone
- 3-Piperidino-4'-butoxypropiophenone
- 4'-Butoxy-3-piperidinopropiophenone
- 4-butoxy-beta-piperidinopropiophenone
- 4-n-butoxy-beta-(1-piperidyl)propiophenone
- CHEBI:4724
- RefChem:55082
- DTXCID6027840
- N01BX02
- R02AD04
- PROPIOPHENONE, 4'-BUTOXY-3-PIPERIDINO-
- DYCLONINE [INN]
- NCGC00016498-01
- CAS-536-43-6
- BRN 0224037
- UNII-078A24Q30O
- Dyclone (Salt/Mix)
- Tanaclone (Salt/Mix)
- Spectrum_001016
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