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SUCCIMER
SynDRA canonical compound SYN0023384 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | DNMT1 |
|---|
| Mechanism of action | Chelating agent |
|---|
| Indication | metal toxicity |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- F2
- ABCB11
- HTR1A
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KCNH2
- HTR2B
- HRH3
- ACHE
- HDAC6
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2A
- ADRA1A
- ADORA1
- TBXA2R
Drug classes
- Antidotes
- Chelating Agents
- Protective Agents
- Sequestering Agents
- Lead Chelating Activity
- Lead Chelator
- Radiopharmaceuticals
- Chelating agent
Cross-references
Synonyms
- CHEMET
- Chemet
- NEPHROSCAN
- meso-2,3-Dimercaptosuccinic acid
- meso-Dimercaptosuccinic acid
- Succimero
- Meso-2,3-dimercaptosuccinic acid
- DIM-SA
- DMS-A
- DMSA
- RO 1-7977
- Dim-sa
- Succimerum
- Dimercaptosuccinic acid
- Succimerum [INN-Latin]
- Succimero [INN-Spanish]
- (R*,S*)-2,3-Dimercaptobutanedioic acid
- UNII-DX1U2629QE
- Succimer [USAN:INN:BAN]
- HSDB 6783
- EINECS 206-155-2
- Ro 1-7977
- BRN 1725150
- DX1U2629QE
- CHEBI:63623
- Butanedioic acid, 2,3-dimercapto-, (R*,S*)-
- meso-2,3-Dimercaptobernsteinsaeure
- dimercaptosuccinic-acid
- 2,3-DIMERCAPTOSUCCINIC ACID, MESO-
- Succinic acid, 2,3-dimercapto-, meso-
- succimer (ii)
- dms
- Ro 1 7977
- meso Dimercaptosuccinic Acid
- Tin Dimercaptosuccinate
- Tin Salt Succimer
- Rhenium Salt Succimer
- Disodium Salt Succimer
Reported adverse events
- Hypersensitivity
- Nausea
- Neutropenia
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