← SynDRA

FLUOROMETHOLONE ACETATE

SynDRA canonical compound SYN0023378 — structure-anchored drug synonym record

All known targets

• NR3C1
• Ar
• PGR

Mechanisms of action (all sources)

• NR3C1 AGONIST
• NR3C1 BINDER

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• NSD2

Drug classes

• Corticosteroid Hormone Receptor Agonists
• Corticosteroid
• Anti-Allergic Agents
• Anti-Inflammatory Agents
• Glucocorticoids
• Hormones

ATC classes

• S01B · ANTIINFLAMMATORY AGENTS
• D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
• D07A · CORTICOSTEROIDS, PLAIN
• D10A · ANTI-ACNE PREPARATIONS FOR TOPICAL USE
• S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
• C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
• CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS

Cross-references

• PubChem CID: 240767
• ChEMBL: CHEMBL1201064
• ChEBI: 78354
• KEGG: D04221
• RxNorm: 221101
• Wikipedia: Fluorometholone_acetate

Synonyms

• FLAREX
• Flarex
• TOBRASONE
• oxylone acetate
• eflone
• Fluorometholone 17-acetate
• NSC-47438
• U-17,323
• U-17323
• Fluorometholone acetate component of tobrasone
• U 17,323
• NSC 47438
• 9I50C3I3OK
• FLUOROMETHOLONE ACETATE (USP MONOGRAPH)
• FLUOROMETHOLONE ACETATE (USP-RS)
• TOBRASONE COMPONENT FLUOROMETHOLONE ACETATE
• U 17323
• Eflone
• UNII-9I50C3I3OK
• AI3-52814
• 6alpha-Methyl-9alpha-fluoro-17-acetoxy-21-deoxyprednisolone
• CHEBI:78354
• EINECS 223-270-3
• Fluorometholone acetate [USAN:USP]
• NSC47438
• Fluorometholone acetate (USAN:USP)
• FLUOROMETHOLONE ACETATE (MART.)
• FLUOROMETHOLONE ACETATE [MART.]
• FLUOROMETHOLONE ACETATE [USP-RS]
• FLUOROMETHOLONE ACETATE [USP MONOGRAPH]
• RefChem:56899
• DTXCID30113915
• FLUOROMETHOLONE ACETATE COMPONENT OF TOBRASONE
• Oxylone acetate
• C24H31FO5
• Flarex (TN)
• SCHEMBL43184

Reported adverse events

• Keratitis
• Cushing's syndrome
• Glaucoma
• Stevens-Johnson syndrome