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BENZTHIAZIDE
SynDRA canonical compound SYN0023357 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CA2 |
|---|
| Mechanism of action | Carbonic anhydrase inhibitor |
|---|
| Indication | edema | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- CA2
- SLC12A3
- CA1
- CA4
- KCNMA1
Mechanisms of action (all sources)
- Carbonic anhydrase inhibitor
- SLC12A3 INHIBITOR
- Thiazide-sensitive sodium-chloride cotransporter inhibitor
- CA2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2A
- ADRA2B
- ADRA2C
- ABCB11
- MC3R
- OPRD1
- NR3C1
- NR1I2
- NPY1R
- MLNR
- MC4R
- KDM4E
- MAOA
- OPRM1
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- OPRK1
- PDE4D
- PDE3A
- HTR1A
- PGR
- PKM
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- SMN1
- TBXA2R
- HTR2A
- HRH1
- HRH2
- ADORA1
- ADORA2A
- ADORA3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2D6
- CP3A4
- CP3A7
- MDR1
- PAFA2
Cross-references
Synonyms
- AQUATAG
- EXNA
- FOVANE
- URESE
- benzothiazide
- dihydrex
- lemazide
- Benztiazida
- Benzothiazide
- NSC-755902
- Aquatag
- Exna
- Fovane
- Urese
- Aquapres
- Aquasec
- Benzotiazida
- Benzthazide
- Benzthiazidum
- Benztiazide
- Dihydrex
- Diucen;Diucene
- Edemex
- Exosalt
- Fouane
- Freeuril
- HyDrine
- Lemazide
- Proaqua
- Regulon
- Urazide
- Benztiazide [DCIT]
- P 1393
- Pfizer 1393
- Aqua-Scrip
- Aquatag (TN)
- Benzotiazida [INN-Spanish]
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