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HYDROCORTISONE PROBUTATE
SynDRA canonical compound SYN0023301 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ANXA1 | NR3C1 |
|---|
| Mechanism of action | glucocorticoid receptor modulator |
|---|
| Indication | dermatosis |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- ANXA1
- NOS2
- NR3C2
- ESRRA
- ESRRB
- ESRRG
- SERPINA6
- KCNA1
- SHBG
- SLC47A1
- FNTA
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 MODULATOR
- Corticosteroid agonist
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Dermatologic Agents
ATC classes
- D07A · CORTICOSTEROIDS, PLAIN
- S01B · ANTIINFLAMMATORY AGENTS
- A07E · INTESTINAL ANTIINFLAMMATORY AGENTS
- S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- A01A · STOMATOLOGICAL PREPARATIONS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- S02B · CORTICOSTEROIDS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
- CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS
Cross-references
Synonyms
- PANDEL
- hydrocortisone buteprate
- pandel
- Hydrocortisone buteprate
- Hydrocortisone butyrate propionate
- Hydrocortisone probutat
- TS-408
- Pandel
- Hydrocortisone 17-butyrate 21-propionate
- O6550D6K3A
- DTXCID6028529
- RefChem:55351
- Hydrocortisone probutate [USAN]
- Hydrocortisone butyrate propionate [JAN]
- Hydrocortisone probutate (USAN)
- Hydrocortisone butyrate propionate (JAN)
- Hydrocortisone probutate;HBP
- UNII-O6550D6K3A
- NCGC00183276-01
- EINECS 276-726-9
- Pandel (TN)
- SCHEMBL4778
- orb1707931
- orb3025470
- CHEBI:31675
- Hydrocortisone buteprate (Standard)
- Tox21_112938
- EBC-27221
- LMST02030128
- MSK163905
- AKOS040740812
- FH23884
- HY-106673R
- MSK163905-100A
- HYDROCORTISONE BUTEPRATE [MART.]
- HYDROCORTISONE BUTEPRATE [VANDF]
- HYDROCORTISONE PROBUTAT [WHO-DD]
- HYDROCORTISONE PROBUTATE [VANDF]
Reported adverse events
- Ototoxicity
- Cushingoid
- Sodium retention
- Hypertension
- Exophthalmos
- Tendon rupture
- Fluid retention
- Vertigo
- Perioral dermatitis
- Epidural lipomatosis
- Central serous chorioretinopathy
- Hypertrichosis
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