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NORGESTIMATE
SynDRA canonical compound SYN0023284 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ESR1 | PGR |
|---|
| Mechanism of action | progesterone receptor agonist |
|---|
| Indication | contraceptive |
|---|
| Disease area | endocrinology |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR3C1
- NR1I2
- SLC6A3
- DRD3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- ADORA1
- HRH2
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A4
- TBXA2R
- TDP1
- HRH3
- HRH1
- ADORA2A
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- IP6K1
- TP53
- SYK
- SMAD3
- SMAD2
- KSYK
- JUN
- GCR
- CP19A
- ESR2
- CP3A7
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- TSHR
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Contraceptives, Oral, Synthetic
- Reproductive Control Agents
- Progestin
ATC classes
- HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- ESTARYLLA
- ESTRADIOL AND NORGESTIMATE
- MILI
- MONO-LINYAH
- NORGESTIMATE AND ETHINYL ESTRADIOL
- ORTHO CYCLEN-21
- ORTHO CYCLEN-28
- ORTHO TRI-CYCLEN
- ORTHO TRI-CYCLEN LO
- PREFEST
- PREVIFEM
- SPRINTEC
- norgestrel oxime acetate
- dexnorgestrel acetime
- Norgestimato
- Dexnorgestrel acetime
- NSC-759159
- ORF-10131
- RWJ-10131
- Norgestimate component of ortho tri-cyclen
- Norgestimate component of prefest
- Norgestimate component of previfem
- Norgestimate component of sprintec
- Norgestimate component of tri lo sprintec
- Norgestimate component of tri-previfem
- Norgestimate component of tri-sprintec
- Norgestimatum
- Norgestrel oxime acetate
- D 138
- Norgestimato [INN-Spanish]
- Norgestimatum [INN-Latin]
- Ortho-Prefest
- Norgestimate (USP/INN)
- Norgestimate [USAN:INN:BAN]
- NKX8DN6TY9
- DTXCID9026922
- CHEBI:50815
- D-138
Reported adverse events
- Headache
- Hepatic adenoma
- Angioedema
- Anxiety
- Breast cancer
- Chest pain
- Hepatitis
- Muscle spasms
- Ovarian cyst
- Pancreatitis
- Syncope
- Tachycardia
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