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PREDNISOLONE TEBUTATE
SynDRA canonical compound SYN0023270 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
| Indication | hemorrhoids |
|---|
| Disease area | General surgery |
|---|
All known targets
- NR3C1
- ADAM17
- AR
- Fabp1
- GLUL
- GPBAR1
- IL6
- NR3C2
- Nr3c1
- PGR
- SERPINA6
- PLA2G1B
Mechanisms of action (all sources)
- NR3C1 AGONIST
- Phospholipase activator
- NR3C1 FULL AGONIST
- NR3C1 MODULATOR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ANDR
- CP2C9
- CP2CJ
- CP2D6
- CP3A7
- ESR2
- ESRRA
- GLI3
- GPR32
- NSD2
- PRGR
- RARA
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Antineoplastic Agents
- Antineoplastic Agents, Hormonal
- Glucocorticoids
- Hormones
- anti-inflammatory agent
- Alkylating Activity
- Alkylating Drug
- Alkylating Agents
- Antineoplastic Agents, Alkylating
ATC classes
- S02B · CORTICOSTEROIDS
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- A01A · STOMATOLOGICAL PREPARATIONS
- D07A · CORTICOSTEROIDS, PLAIN
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
- L01A · ALKYLATING AGENTS
- A07E · INTESTINAL ANTIINFLAMMATORY AGENTS
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- S01B · ANTIINFLAMMATORY AGENTS
- S01C · ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
- CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS
Cross-references
Synonyms
- HYDELTRA-TBA
- prednisolone tert-butylacetate
- Prednisolone TBA
- prednisolone butylacetate
- prednisolone tertiary butylacetate
- Prednisolone 21-tert-butylacetate
- Anhydrous prednisolone tebutate
- Prednisolone butylacetate
- Hydeltra-tba
- Hydeltra-TBA
- Prednisolone Butylacetate
- Prednisolone tertiary butylacetate
- 1V7A1U282K
- DTXCID303505
- Codelcortone TBA
- RefChem:55913
- prednisolone tertiary butyl acetate
- Hydeltra-T.B.A.
- EINECS 231-661-5
- UNII-1V7A1U282K
- Predalone T.B.A.
- Prednisolone tebutate [USP]
- MFCD00867455
- Hydeltra-TBA (TN)
- Prednisolone butyl acetete
- SCHEMBL40845
- CHEBI:8381
- orb1708816
- Prednisolone Tebutate (Standard)
- Prednisolone tebutate (JAN/USP)
- HY-U00098R
- PREDNISOLONE TEBUTATE [JAN]
- Tox21_113662
- EBC-27151
- EX-A11118
- HY-U00098
Reported adverse events
- Cushingoid
- Exophthalmos
- Fluid retention
- Urticaria
- Hypertension
- Sodium retention
- Petechiae
- Headache
- Vertigo
- Glaucoma
- Infection
- Tendon rupture
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