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METYROSINE
SynDRA canonical compound SYN0023240 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TH |
|---|
| Mechanism of action | tyrosine hydroxylase inhibitor |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- TH INHIBITOR
- Tyrosine 3-hydroxylase inhibitor
- tyrosine hydroxylase inhibitor
- TH BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- NPY2R
- MPHOSPH8
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDR
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- NPY1R
- NR3C1
- FLT1
- OPRD1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- PTPRC
Drug classes
- Catecholamine Synthesis Inhibitors
- Catecholamine Synthesis Inhibitor
- Enzyme Inhibitors
ATC classes
- C02K · OTHER ANTIHYPERTENSIVES
Cross-references
Synonyms
- DEMSER
- Demser
- metirosine
- demser
- L-Metyrosine
- Metirosine
- Metirosina
- Methyltyrosine
- Racemetirosine, (s)-
- L-588357-0
- MK-781
- Metirosinum
- Racemetirosina
- Racemetirosine
- Racemetirosinum
- Metyrosine[USAN]
- Racemetirosine [INN]
- M 8131
- Alpha-MPT
- Alpha-Methyltyrosine
- Demser (TN)
- H 9/88
- L-AMPT
- M-5185
- Metirosina [INN-Spanish]
- Metirosine (INN)
- Metirosinum [INN-Latin]
- Metyrosine (USP)
- Racemetirosina [INN-Spanish]
- Racemetirosinum [INN-Latin]
- DL-alpha-Methyltyrosine
- Alpha-Methyl-L-tyrosine
- Alpha-Methyl-dl-tyrosine
- Alpha-Methyl-p-tyrosine
- Alpha-Methyl-para-tyrosine
- A-methyl-L-p-tyrosine
- Alpha-Methyl-L-P-Tyrosine
Reported adverse events
- Anxiety
- Crystalluria
- Sedation
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