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RIMEXOLONE
SynDRA canonical compound SYN0023090 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | Glucocorticoid receptor agonist |
|---|
| Indication | anterior uveitis |
|---|
| Disease area | ophthalmology |
|---|
All known targets
Mechanisms of action (all sources)
- NR3C1 AGONIST
- ESRRA MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- PGR
- CNR1
- ADORA1
- HTR2B
- HTR2C
- HTR3A
- IDH1
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NFE2L2
- NPY1R
- OPRD1
- HTR1A
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HTR2A
- HRH2
- ADORA2A
- BDKRB2
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Glucocorticoids
- Hormones
ATC classes
- H02A · CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
- S01B · ANTIINFLAMMATORY AGENTS
Cross-references
Synonyms
- VEXOL
- rimexel
- trimexolone
- Rimexolona
- Rimexolon
- ORG-6216
- Vexol
- Rimexolone (sustained release intra-articular steroid suspension, Plexis, arthritis)
- Org 6216
- MLS002154105
- Rimexel
- O7M2E4264D
- Trimexolone
- Rimexolonum
- Rimexolonum [INN-Latin]
- Rimexolona [INN-Spanish]
- UNII-O7M2E4264D
- Rimexolone [USAN:USP:INN:BAN]
- Vexol (TN)
- AL 02178
- RIMEXOLONE [MI]
- Rimexolone (USP/INN)
- RIMEXOLONE [INN]
- Prestwick0_001020
- Prestwick1_001020
- Prestwick2_001020
- Prestwick3_001020
- RIMEXOLONE [USAN]
- RIMEXOLONE [VANDF]
- RIMEXOLONE [MART.]
- RIMEXOLONE [USP-RS]
- RIMEXOLONE [WHO-DD]
- BSPBio_001179
- SCHEMBL445300
- SPBio_003050
- BPBio1_001297
- GTPL7099
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